Reduced Sulfotransferase SULT2A1 Activity in Patients With Alzheimer´s Disease
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023761%3A_____%2F15%3A%230000573" target="_blank" >RIV/00023761:_____/15:#0000573 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/15:43910502 RIV/00216208:11110/15:10313568 RIV/00216208:11240/15:10313568 RIV/00064190:_____/15:#0001073 RIV/00064165:_____/15:10313568
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Reduced Sulfotransferase SULT2A1 Activity in Patients With Alzheimer´s Disease
Original language description
Steroids are important components in the pathophysiology of Alzheimer's disease (AD). Although their role has been studied, the corresponding metabolomic data is limited. In the present study we evaluate the role of steroid sulfotransferase SULT2A1 in the pathophysiology of AD on the basis of circulating steroids (measured by GC-MS), in which the sulfation catalyzed by SULT2A1 dominates over glucuronidation (pregnenolone/sulfate, DHEA/sulfate, androstenediol/sulfate and 5alpha-reduced pregnane and androstane catabolites).
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT13543" target="_blank" >NT13543: Study of Common Pathogenetic Factors of Alzheimer Disease and Type 2 Diabetes Mellitus</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Physiological Research
ISSN
0862-8408
e-ISSN
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Volume of the periodical
64
Issue of the periodical within the volume
Suppl.2
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
9
Pages from-to
"S265"-"S273"
UT code for WoS article
000365011800022
EID of the result in the Scopus database
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