Release of Bisphenol A from Milled and 3D-Printed Dental Polycarbonate Materials

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023761%3A_____%2F21%3AN0000030" target="_blank" >RIV/00023761:_____/21:N0000030 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/21:10433220 RIV/00064165:_____/21:10433220

Result on the web

<a href="https://www.mdpi.com/1996-1944/14/19/5868/htm" target="_blank" >https://www.mdpi.com/1996-1944/14/19/5868/htm</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/ma14195868" target="_blank" >10.3390/ma14195868</a>

Result language

angličtina

Original language name

Release of Bisphenol A from Milled and 3D-Printed Dental Polycarbonate Materials

Original language description

Polycarbonates are polymers of bisphenol A (BPA), a well-known endocrine disruptor. This study evaluated the release of BPA from polycarbonate crowns that were (1) milled from Temp Premium Flexible (ZPF, Zirkonzahn, Italy) or Tizian Blank Polycarbonate (TBP, Schutz Dental, Germany), or (2) 3D-printed (Makrolon 2805, Covestro, Germany). Commercial prefabricated polycarbonate crowns (3M, USA) and milled poly(methyl methacrylate) (PMMA) crowns (Temp Basic, Zirkonzahn, Italy) were included for comparison. The crowns were stored at 37 & DEG;C in artificial saliva (AS) or methanol, which represented the worst-case scenario of BPA release. Extracts were collected after 1 day, 1 week, 1 month and 3 months. BPA concentrations were measured using liquid chromatography-tandem mass spectrometry. The amounts of released BPA were expressed in micrograms per gram of material (mu g/g). After 1 day, the highest amounts of BPA were measured from milled polycarbonates, TBP (methanol: 32.2 & PLUSMN; 3.8 mu g/g, AS: 7.1 & PLUSMN; 0.9 mu g/g) and ZPF (methanol 22.8 & PLUSMN; 7.7 mu g/g, AS: 0.3 & PLUSMN; 0.03 mu g/g), followed by 3D-printed crowns (methanol: 11.1 & PLUSMN; 2.3 mu g/g, AS: 0.1 & PLUSMN; 0.1 mu g/g) and prefabricated crowns (methanol: 8.0 & PLUSMN; 1.6 mu g/g, AS: 0.07 & PLUSMN; 0.02 mu g/g). Between 1 week and 3 months, the average daily release of BPA in methanol and AS decreased below 2 mu g/g and 0.6 mu g/g, respectively. No BPA was released from PMMA in AS, and the cumulative amount released in methanol was 0.2 & PLUSMN; 0.06 mu g/g. In conclusion, polycarbonates could be a relevant source of BPA, but the current tolerable daily intake of BPA (4 mu g/kg body weight) should not be exceeded.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10403 - Physical chemistry

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

MATERIALS

ISSN

1996-1944

e-ISSN

1996-1944

Volume of the periodical

14

Issue of the periodical within the volume

19

Country of publishing house

CH - SWITZERLAND

Number of pages

14

Pages from-to

5868

UT code for WoS article

000727371100001

EID of the result in the Scopus database

2-s2.0-85117022652