People with newly diagnosed multiple sclerosis benefit from a complex preventative intervention—a single group prospective study with follow up
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023761%3A_____%2F24%3AN0000029" target="_blank" >RIV/00023761:_____/24:N0000029 - isvavai.cz</a>
Alternative codes found
RIV/60460709:41330/24:101209 RIV/00216208:11120/24:43926934 RIV/00064173:_____/24:43926934
Result on the web
<a href="https://doi.org/10.3389/fneur.2024.1373401" target="_blank" >https://doi.org/10.3389/fneur.2024.1373401</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/fneur.2024.1373401" target="_blank" >10.3389/fneur.2024.1373401</a>
Alternative languages
Result language
angličtina
Original language name
People with newly diagnosed multiple sclerosis benefit from a complex preventative intervention—a single group prospective study with follow up
Original language description
Background: Newly diagnosed people with multiple sclerosis frequently report fatigue, pain, depression and anxiety. Preventative programmes may be beneficial, but there is limited evidence of their effectiveness, especially long-term follow-up. Methods: The programme consisted of 6-month face to face intervention (an introductory workshop, psychology-led group sessions and individual physical therapy) followed by 6-month self-guided therapy. Outcome measures were taken at baseline, 6 and 12 months. Primary outcomes measures were self-report questionnaires for fatigue, satisfaction with life and disease acceptance. Secondary outcomes were spirometry, spiroergometric parameters and neuroactive steroid levels. Results: From 22 participants enrolled, 17 completed the first 6 months and 13 the follow-up. Fatigue measured on the Fatigue scale for motor and cognitive functions decreased significantly at 6 months (p = 0.035) and at follow-up (p = 0.007). The Modified Fatigue Impact Scale (p = 0.035) and Satisfaction With Life Scale (p = 0.007) significantly increased at follow-up. Spirometry, spiroergometric parameters, steroid hormones and neuroactive steroids levels did not change significantly. Conclusion: This programme reduces fatigue and improves satisfaction with life in this patient group with improvements sustained at 12 months. People who participated more frequently showed greater benefit. Clinical rehabilitation impact: The paper describes the effects of a complex preventative intervention for people with newly diagnosed Multiple Sclerosis. The study found that this programme reduces fatigue and improves satisfaction with life with long-term benefit (at 12-month follow up). The individuals who participated less frequently experienced fewer benefits.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30306 - Sport and fitness sciences
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Frontiers in Neurology
ISSN
1664-2295
e-ISSN
1664-2295
Volume of the periodical
15
Issue of the periodical within the volume
April
Country of publishing house
CH - SWITZERLAND
Number of pages
8
Pages from-to
1373401
UT code for WoS article
001206715800001
EID of the result in the Scopus database
2-s2.0-85191090491