An easy way to increase confidence in beta-amyloid PET evaluation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023884%3A_____%2F12%3A00007287" target="_blank" >RIV/00023884:_____/12:00007287 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.5603/NMR.2017.0019" target="_blank" >http://dx.doi.org/10.5603/NMR.2017.0019</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5603/NMR.2017.0019" target="_blank" >10.5603/NMR.2017.0019</a>
Alternative languages
Result language
angličtina
Original language name
An easy way to increase confidence in beta-amyloid PET evaluation
Original language description
BACKGROUND: In patients with brain atrophy, it is not easy to distinguish pathologic uptake of flutemetamol (FMM) in the gray matter from nonspecific, physiologic uptake in the white matter. In this paper we suggest an easy image processing method. MATERIAL AND METHODS: The proof-of-concept study involved three patients with mild cognitive impairment and different graphical findings at FMM-PET. Two-phase FMM-PET was acquired; the early phase represented the perfusion of gray matter, while the late phase depicted the white matter and beta-amyloid load in the gray matter. The border of the gray matter was easily extracted from the early-phase images using thresholding and the isocontour “Edges” color table. The late phase was registered with the edge images of the early phase and displayed using alpha-blending. RESULTS: Early- and late-phase image fusion displayed with appropriate color tables is presented in three different cases to illustrate the added value of the suggested approach. CONCLUSIONS: Composite late-phase images with enhanced gray matter borders strongly facilitate assessment of beta-amyloid presence in the gray matter. This is especially helpful in patients with brain atrophy.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30224 - Radiology, nuclear medicine and medical imaging
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nuclear Medicine Review CEE
ISSN
1506-9680
e-ISSN
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Volume of the periodical
20
Issue of the periodical within the volume
2
Country of publishing house
PL - POLAND
Number of pages
3
Pages from-to
107-109
UT code for WoS article
000402430100010
EID of the result in the Scopus database
2-s2.0-85019668503