Brugada syndrome – Case report, risk stratification and treatment
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023884%3A_____%2F16%3A00007716" target="_blank" >RIV/00023884:_____/16:00007716 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.crvasa.2016.01.011" target="_blank" >http://dx.doi.org/10.1016/j.crvasa.2016.01.011</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.crvasa.2016.01.011" target="_blank" >10.1016/j.crvasa.2016.01.011</a>
Alternative languages
Result language
angličtina
Original language name
Brugada syndrome – Case report, risk stratification and treatment
Original language description
Brugada syndrome (BrS) is a malignant, genetically-determined, arrhythmogenic syndrome that is characterized by abnormal electrocardiogram (ECG) findings and an increased risk of sudden cardiac death (SCD). BrS is responsible for about 4% of all sudden deaths and up to 20% of sudden deaths among patients with structurally normal hearts. Since the first report on BrS in 1992 by the Spanish cardiologists Pedro and Josep Brugada, there are still some unresolved clinical problems as risk stratification (RS) and identification of those patients at high risk of SCD who need implantable cardioverter-defibrillator (ICD). All recommendations are based on expert opinion, there is still no validated algorithm for RS of asymptomatic patients (low prevalence, no randomized controlled trials). Electro-anatomic mapping studies have revealed, for the first time, an arrhythmogenic substrate over the right ventricular outflow tract (RVOT) in BrS patients. Better understanding of the genetic and electrophysiological changes underlying BrS are needed for RS of asymptomatic BrS patients in preventing morbidity and mortality. In this article we present a case of 42-year old man with Brugada type ECG that was recorded after sudden cardiac arrest and briefly summarize current knowledge about the ECG based methods for diagnosis and emphasize risk factors for RS and options in treatment BrS patients. (C) 2016 The Czech Society of Cardiology. Published by Elsevier Sp. zo.o. All rights reserved.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
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Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cor et Vasa
ISSN
0010-8650
e-ISSN
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Volume of the periodical
58
Issue of the periodical within the volume
5
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
6
Pages from-to
491-496
UT code for WoS article
000410027900009
EID of the result in the Scopus database
2-s2.0-84961225978