Nanoparticle-specific changes in Arabidopsis thaliana gene expression after exposure to ZnO, TiO2, and fullerene soot

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027006%3A_____%2F12%3A00002262" target="_blank" >RIV/00027006:_____/12:00002262 - isvavai.cz</a>
Alternative codes found
RIV/61389030:_____/12:00389142
Result on the web
<a href="http://dx.doi.org/10.1016/j.jhazmat.2012.08.059" target="_blank" >http://dx.doi.org/10.1016/j.jhazmat.2012.08.059</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jhazmat.2012.08.059" target="_blank" >10.1016/j.jhazmat.2012.08.059</a>

Result language
angličtina
Original language name
Nanoparticle-specific changes in Arabidopsis thaliana gene expression after exposure to ZnO, TiO2, and fullerene soot
Original language description
The effect of exposure to 100 mg/L zinc oxide (nZnO), fullerene soot (FS) or titanium dioxide (nTiO2)nanoparticles on gene expression in Arabidopsis thaliana roots was studied using microarrays. After 7 d,nZnO, FS, or nTiO2 exposure resulted in 660 up- and 826 down-regulated genes, 232 up- and 189 downregulated genes, and 80 up- and 74 down-regulated genes, respectively (expression difference > 2-fold; p[t test] < 0.05). The genes induced by nZnO and FS include mainly ontology groups annotated as stressresponsive, including both abiotic (oxidative, salt, water deprivation) and biotic (wounding and defense to pathogens) stimuli. The down-regulated genes upon nZnO exposure were involved in cell organization and biogenesis, including translation, nucleosome assembly and microtubule based process. FS largely repressed the transcription of genes involved in electron transport and energy pathways. Only mild changes in gene expression were observed upon nTiO2 exposure, which resulted in up-
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Project
<a href="/en/project/LH11047" target="_blank" >LH11047: Plants and Nanoparticles - Friends or Foes?</a><br>
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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