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Differential allergen expression in three Tyrophagus putrescentiae strains inhabited by distinct microbiome

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027006%3A_____%2F19%3A00005551" target="_blank" >RIV/00027006:_____/19:00005551 - isvavai.cz</a>

  • Result on the web

    <a href="https://onlinelibrary.wiley.com/doi/abs/10.1111/all.13921?af=R" target="_blank" >https://onlinelibrary.wiley.com/doi/abs/10.1111/all.13921?af=R</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1111/all.13921" target="_blank" >10.1111/all.13921</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Differential allergen expression in three Tyrophagus putrescentiae strains inhabited by distinct microbiome

  • Original language description

    The domestic mite, Tyrophagus putrescentiae, is a medically important, ubiquitous pest that commonly occurs in stored food and house dust, causing allergies. We analyzed the transcriptomes of three strains of T. putrescentiae, each harboring a different microbiome. These mite strains were analyzed at a level representative of a natural population using seven replicates. We found 78 transcripts belonging to 8 allergen groups known in T. putrescentiae (2, 3, 10, 13, 28, 34, 35 and 36) and identified 16 putative allergen groups previously unknown for this mite species (4, 5, 6, 7, 8, 11, 14, 16, 20, 24, 25, 27, 30, 31, 33 and 38). We documented polymorphism and differences in the expression level of these transcripts. Most importantly, the expression of several allergens (group 4, 7, 10, 11, 13, 20 and 36) was correlated with the presence of common intracellular bacterial symbionts, Wolbachia and Blattabacterium-like bacteria. The largest differences in allergen expression among the strains were found in allergen groups 2, 10, and 13 (known allergens) and groups 4 and 14 (putative allergens). We suggest that allergen production in T. putrescentiae may be affected by its microbiome composition.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10618 - Ecology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Allergy

  • ISSN

    0105-4538

  • e-ISSN

  • Volume of the periodical

    74

  • Issue of the periodical within the volume

    12

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    6

  • Pages from-to

    2502-2507

  • UT code for WoS article

    000517148400024

  • EID of the result in the Scopus database

    2-s2.0-85067461038