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Epigenetic analysis of human spermatozoa after their injection into ovulated mouse oocytes

Result description

The epigenetic status of human spermatozoa is difficult to analyse. The method of interspecies fertilization is widely used for different purposes. In our experiments, we have adopted this approach for the analysis of epigenetic status of human spermatozoa after their injection into ovulated mouse oocytes. Our model system allows us to evaluate some epigenetic parameters of spermatozoa. This method can thus be used for different fertility assessment purposes.

Keywords

spermatozoaoocytesepigenetics

The result's identifiers

Alternative languages

  • Result language

    angličtina

  • Original language name

    Epigenetic analysis of human spermatozoa after their injection into ovulated mouse oocytes

  • Original language description

    The epigenetic status of human spermatozoa is difficult to analyse. The method of interspecies fertilization is widely used for different purposes. In our experiments, we have adopted this approach for the analysis of epigenetic status of human spermatozoa after their injection into ovulated mouse oocytes. Our model system allows us to evaluate some epigenetic parameters of spermatozoa. This method can thus be used for different fertility assessment purposes.

  • Czech name

    Epigenetické hodnocení spermií po jejich injekci do ovulovaných oocytů myši

  • Czech description

    Epigenetické parametry spermií lze jen těžko analyzovat. Vyvinuli jsme proto metodu mezidruhového oplození, kdy lidské spermie byly injikovány do ovulovaných vajec myší. Pomoci tohoto modelového postupu lze analyzovat epigenetické parametry spermií a lzetak tuto metodu použít v řadě embryobiotechnologických postupů.

Classification

  • Type

    Jx - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Human Reproduction

  • ISSN

    0268-1161

  • e-ISSN

  • Volume of the periodical

    23

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    8

  • Pages from-to

  • UT code for WoS article

    000253746900022

  • EID of the result in the Scopus database

Result type

Jx - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

Jx

CEP

EB - Genetics and molecular biology

Year of implementation

2008