The maternal nucleolus plays a key role in centromere satellite maintenance during the oocyte to embryo transition

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027014%3A_____%2F14%3A%230001985" target="_blank" >RIV/00027014:_____/14:#0001985 - isvavai.cz</a>
Result on the web
<a href="http://www.vuzv.cz/sites/File/_privat/14030.pdf" target="_blank" >http://www.vuzv.cz/sites/File/_privat/14030.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1242/dev.105940" target="_blank" >10.1242/dev.105940</a>

Result language
angličtina
Original language name
The maternal nucleolus plays a key role in centromere satellite maintenance during the oocyte to embryo transition
Original language description
The oocyte (maternal) nucleolus is essential for early embryonic development and embryos originating from enucleolated oocytes arrest at the 2-cell stage. The reason for this is unclear. We demonstrated that whereas rRNA transcription activation and pre-rRNA processing are unaffected by the absence of NPB, this organelle is essential for the regulation of major and minor satellite sequences and consequently for normal development.
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
—

Project
<a href="/en/project/GPP302%2F11%2FP069" target="_blank" >GPP302/11/P069: The role of the nucleolus precursor body in oogenesis and early embryonic development</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)