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Laser microdissection and laser pressure catapulting for the generation of chromosome-specific paint probes of domestic animals

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F01%3A80000039" target="_blank" >RIV/00027162:_____/01:80000039 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Laser microdissection and laser pressure catapulting for the generation of chromosome-specific paint probes of domestic animals

  • Original language description

    PALM microlaser technology was used to generate bovine, porcine and equine chromosome paint probes. Single chromosomes were isolated by laser dissection of the membrane around the target chromosome and 10-15 copies of the chromosome were collected by catapulting them into the Eppendorf cap. The microdissected DNA was amplified by degenerate oligonucleotide-primed PCR. The amplification product was labelled with digoxigenin and spectrum orange in secondary PCR, or by Biotin Chem-Link, and hybridized ontometaphase spreads. Fluorescence in situ hybridization signal revealed specific painting of the chromosome. Paint probes generated by this method are presented.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA523%2F98%2F0261" target="_blank" >GA523/98/0261: Investigations into aneuploides in gametes and embryos of farm animals using the in situ fluorescence hybridization technique</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2001

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    14th International Chromosome Conference, Chromosome research

  • ISSN

    0967-3849

  • e-ISSN

  • Volume of the periodical

    9

  • Issue of the periodical within the volume

    suppl.1

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    1

  • Pages from-to

    69

  • UT code for WoS article

  • EID of the result in the Scopus database