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Antigen-specific immune response of piglets to experimental infection with Mycobacterium avium ssp. avium and Mycobacterium avium ssp. hominissuis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F08%3A%230000392" target="_blank" >RIV/00027162:_____/08:#0000392 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Antigen-specific immune response of piglets to experimental infection with Mycobacterium avium ssp. avium and Mycobacterium avium ssp. hominissuis

  • Original language description

    The aim of the study was to bring new information about production of antigen-specific antibodies and cell-mediated immunity measured as prodution of interferon-gamma after in vitro stimulation with a specific antigen in piglets experimentally infected with Mycobacterium avium ssp. avium (MAA) and Mycobacterium avium ssp. hominissuis (MAH). From the results obtained, it is clear that MAA-infected piglets mounted both antibody and cell-mediated immunity. Contrary to that, MAH-infected animals responded by a low intensity of cell-mediated imunity only. Therefore, detection of a specific antigen-induced interferon-gamma production could be very useful easily performed methods for an intravital diagnosis of mycobacterial infection in pigs.

  • Czech name

    Specifická imunitní odpověď selat na experimentální infekci Mycobacterium avium ssp. avium and Mycobacterium avium ssp. hominissuis

  • Czech description

    Cílem studie bylo přinést nové informace o produkci antigenně specifických protilátek a buňkami zprostředkované imunity měřené jako produkce interferonu-gama po in vitro stimulaci specifickým antigenem u selat experimentálně infikovaných Mycobacterium avium ssp. avium (MAA) a Mycobacterium avium ssp. hominissuis (MAH). Ze získaných výsledků je patné, že MAA infikovaná selata produkovala i protilátkovou i buňkami zprostředkovanou imunitu. Naopak, MAH infikovaná selata odpovídala pouze nízkou intenzitou buňkami zprostředkované imunity. Detekce produkce interferonu gama po in vitro stimulaci spefickým antigenem může být užitečná snadno proveditelná metoda intravitální diagnostiky mykobacteriálních infekcí u prasat.

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    GJ - Diseases and animal vermin, veterinary medicine

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/1B53009" target="_blank" >1B53009: Avian tuberculosis and mycobacterioses: the development of methods for theirs prevention and eradication by study of mycobacterial sources and pathogenesis of infection</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    20th International Pig Veterinary Society Congress

  • ISBN

    978-0-620-41364-0

  • ISSN

  • e-ISSN

  • Number of pages

    1

  • Pages from-to

  • Publisher name

    Hein Jonker Media Management

  • Place of publication

    Durban, South Africa

  • Event location

    Durban, South Africa

  • Event date

    Jun 22, 2008

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article