Expression of macrophage CD44 receptor in the course of experimental inflammatory response of bovinne mammary gland induced by lipopolysaccharide and muramyl dipeptide

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F09%3A%230000490" target="_blank" >RIV/00027162:_____/09:#0000490 - isvavai.cz</a>

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Expression of macrophage CD44 receptor in the course of experimental inflammatory response of bovinne mammary gland induced by lipopolysaccharide and muramyl dipeptide

Original language description

The aim of this study was to investigate development over time of the surface expression of CD44 on macrophages during an inflammatory response of bovine mammary gland. Intramammary instillation of muramyl dipeptide (MDP) and lipopolysaccharide (LPS) resulted in a significant increase in the total count of CD44+ non-vacuolised macrophages ((N)MAC) after 24 h. During resolution of the inflammatory response, there was observed a gradual decrease in the total count CD44+ (N)MAC. The lower total count and proportion of CD44 + vacuolised macrophages ((V)MAC) was observed as the effect of MDP and LPS at 24 h after induction (P<0.01). During resolution, the total count and proportion of CD44 + (V)MAC increased. We have demonstrated CD44 receptor is expressedduring the inflammatory response caused by LPS and MDP and the effect of these components on CD44 expression was particularly evident during initiation of the inflammatory response.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

GJ - Diseases and animal vermin, veterinary medicine

OECD FORD branch

—

Project

<a href="/en/project/GA524%2F03%2F1531" target="_blank" >GA524/03/1531: The role of mononuclear phagocytes during the acute inflammation of the bovine mammary gland</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Research in Veterinary Science

ISSN

0034-5288

e-ISSN

—

Volume of the periodical

86

Issue of the periodical within the volume

2

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

—

UT code for WoS article

000264244800009

EID of the result in the Scopus database

—