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Expression of macrophage CD44 receptor in the course of experimental inflammatory response of bovine mammary gland induced by lipopolysaccharide and muramyl dipeptide

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F09%3A00128002" target="_blank" >RIV/62156489:43210/09:00128002 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.rvsc.2008.07.016" target="_blank" >http://dx.doi.org/10.1016/j.rvsc.2008.07.016</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.rvsc.2008.07.016" target="_blank" >10.1016/j.rvsc.2008.07.016</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Expression of macrophage CD44 receptor in the course of experimental inflammatory response of bovine mammary gland induced by lipopolysaccharide and muramyl dipeptide

  • Original language description

    The aim of this study was to investigate development over time of the surface expression of CD44 on macrophages during an inflammatory response of bovine mammary gland. Intramammary instillation of muramyl dipeptide (MDP) and lipopolysaccharide (LPS) resulted in a significant increase in the total count of CD44+ non-vacuolized macrophages (NMAC) after 24 hours. During resolution of the inflammatory response, there was observed a gradual decrease in the total count CD44+NMAC. The lower total count and proportion of CD44+ vacuolized macrophages (VMAC) was observed as the effect of MDP and LPS at 24 hours after induction (P<0.01). During resolution, the total count and proportion of CD44+VMAC increased. We have demonstrated CD44 receptor is expressed during the inflammatory response caused by LPS and MDP and the effect of these components on CD44 expression was particularly evident during initiation of the inflammatory response. High expression of CD44 in resolution of inflammatory respon

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    GJ - Diseases and animal vermin, veterinary medicine

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Research in Veterinary Science

  • ISSN

    0034-5288

  • e-ISSN

  • Volume of the periodical

    86

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    6

  • Pages from-to

    235-240

  • UT code for WoS article

    264244800009

  • EID of the result in the Scopus database