Nanofibers in mucosal drug and vaccine delivery
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F20%3AN0000008" target="_blank" >RIV/00027162:_____/20:N0000008 - isvavai.cz</a>
Result on the web
<a href="https://www.intechopen.com/books/nanomaterials-toxicity-human-health-and-environment/nanofibers-in-mucosal-drug-and-vaccine-delivery" target="_blank" >https://www.intechopen.com/books/nanomaterials-toxicity-human-health-and-environment/nanofibers-in-mucosal-drug-and-vaccine-delivery</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5772/intechopen.82279" target="_blank" >10.5772/intechopen.82279</a>
Alternative languages
Result language
angličtina
Original language name
Nanofibers in mucosal drug and vaccine delivery
Original language description
Successful mucosal administration and delivery of drugs still pose a great challenge. However, the possibility to deliver not only small drug molecules, but also macromolecular drugs and nanoparticles via mucosal surfaces represents a great opportunity. Rapid onset of drug action, avoidance of first-pass metabolism, and high immunocompetence of mucosa are some of the important features for mucosal drug and vaccine delivery. The use of mucoadhesive drug delivery systems, systems with fast-dissolving properties, and nanomaterials with mucus penetration properties are examples of successful strategies to achieve effective mucosal drug and vaccine delivery. Non-keratinised mucosa of the oral cavity, the nasal and vaginal mucosa represent favourable sites of drug administration. Polymer nanofibers have attracted much attention because of remarkable characteristics such as a large surface area to volume ratio and high porosity. Nanofibers have been extensively used for different biomedical applications including wound dressing, tissue engineering and drug delivery. Among their fabrication methods, the introduction of electrospinning technique was an important step towards achieving the goal of large scale industrial production of nanofiber-based drug delivery systems used in mucosal applications. This chapter provides an overview on all aspects of mucosal drug and vaccine delivery using nanofibers.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
20101 - Civil engineering
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Nanomaterials: Toxicity, Human Health and Environment
ISBN
978-1-78984-616-4
Number of pages of the result
28
Pages from-to
171-198
Number of pages of the book
231
Publisher name
IntechOpen
Place of publication
London, UK
UT code for WoS chapter
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