Nanofibers in Mucosal Drug and Vaccine Delivery

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24620%2F18%3A00005925" target="_blank" >RIV/46747885:24620/18:00005925 - isvavai.cz</a>

Result on the web

<a href="https://www.intechopen.com/online-first/nanofibers-in-mucosal-drug-and-vaccine-delivery/" target="_blank" >https://www.intechopen.com/online-first/nanofibers-in-mucosal-drug-and-vaccine-delivery/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5772/intechopen.82279" target="_blank" >10.5772/intechopen.82279</a>

Result language

angličtina

Original language name

Nanofibers in Mucosal Drug and Vaccine Delivery

Original language description

Successful mucosal administration and delivery of drugs still pose a great challenge. However, the possibility to deliver not only small drug molecules but also macromolecular drugs and nanoparticles via mucosal surfaces represents a great opportunity. Rapid onset of drug action, avoidance of first-pass metabolism, and high immunocompetence of mucosa are some of the important features for mucosal drug and vaccine delivery. The use of mucoadhesive drug delivery systems, systems with fast dissolving properties, and nanomaterials with mucus penetration properties are examples of successful strategies to achieve effective mucosal drug and vaccine delivery. Non-keratinized mucosa of the oral cavity, the nasal and vaginal mucosa represent favorable sites of drug administration. Polymer nanofibers have attracted much attention because of remarkable characteristics such as a large surface area to volume ratio and high porosity. Nanofibers have been extensively used for different biomedical applications including wound dressing, tissue engineering, and drug delivery. Among their fabrication methods, the introduction of electrospinning technique was an important step toward achieving the goal of large scale industrial production of nanofiber-based drug delivery systems used in mucosal applications. This chapter provides an overview on all aspects of mucosal drug and vaccine delivery using nanofibers.

Czech name

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Czech description

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Type

C - Chapter in a specialist book

CEP classification

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OECD FORD branch

21001 - Nano-materials (production and properties)

Project

<a href="/en/project/LO1201" target="_blank" >LO1201: DEVELOPMENT OF THE INSTITUTE FOR NANOMATERIALS, ADVANCED TECHNOLOGIES AND INNOVATION</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Book/collection name

Nanofibers - from Preparation to Applications

ISBN

978-953-51-6328-2

Number of pages of the result

28

Pages from-to

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Number of pages of the book

28

Publisher name

Intechopen

Place of publication

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UT code for WoS chapter

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