Carbapenemase-Producing Gram-Negative Bacteria from American Crows in the United States
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F21%3AN0000007" target="_blank" >RIV/00027162:_____/21:N0000007 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/21:00122205 RIV/62157124:16170/21:43879602 RIV/62157124:16810/21:43879602 RIV/62157124:16270/21:43879602
Result on the web
<a href="https://aac.asm.org/content/65/1/e00586-20" target="_blank" >https://aac.asm.org/content/65/1/e00586-20</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1128/AAC.00586-20" target="_blank" >10.1128/AAC.00586-20</a>
Alternative languages
Result language
angličtina
Original language name
Carbapenemase-Producing Gram-Negative Bacteria from American Crows in the United States
Original language description
This study was focused on wild corvid species as a reservoir of carbapenemase-producing Gram-negative bacteria in the USA. From a total of 590 faecal samples of American crow, eleven Providencia rettgeri isolates harbouring blaIMP-27 gene, an isolate of Klebsiella pneumoniae sequence type (ST) 258 with blaKPC-2 and an isolate of Enterobacter cloacae complex with blaIMI-1 were obtained by selective cultivation on meropenem-supplemented media followed by PCR detection of carbapenemase-encoding genes and whole-genome sequencing. P. rettgeri isolates were assigned to two phylogenetically unrelated clusters harbouring blaIMP-27 gene located on the chromosome as a class 2 integron gene cassette within Tn7 transposon. K. pneumoniae ST258 isolate showed a multi-drug resistance profile and carried blaKPC-2 on a pKpQIL-like plasmid as a part of Tn4401a. The phylogenetic comparison of 237 genomes of K. pneumoniae ST258 obtained from BIGSdb database showed high similarity of the corvid isolate to human isolates. In E. cloacae complex isolate, the gene blaIMI-1 was located within an integrative mobile element exploiting the Xer recombinases, EcloIMEX-2. Despite that we observed the low prevalence (4.7%, n=277) of Gram-negative bacteria with carbapenemase genes in corvids in the USA, the outcome of the study highlights the role of anthropogenic derived dissemination of carbapenemase-producing bacteria to wildlife and raise attention to corvids as possible environmental vector of bacteria resistant to critically important antimicrobials.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10606 - Microbiology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Antimicrobial Agents and Chemotherapy
ISSN
0066-4804
e-ISSN
1098-6596
Volume of the periodical
65
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
19
Pages from-to
—
UT code for WoS article
000600658500005
EID of the result in the Scopus database
2-s2.0-85098669102