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Providencia rettgeri with IMP-27 carbapenemase from American crows

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16810%2F18%3A43876821" target="_blank" >RIV/62157124:16810/18:43876821 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Providencia rettgeri with IMP-27 carbapenemase from American crows

  • Original language description

    A total of 277 Gram-negative bacteria, obtained from faecal specimens of American crow (Corvus brachyrhynchos) in USA, with reduced susceptibility to meropenem (&gt;0.125 mg/L) were tested for the presence of carbapenemase encoding gene blaIMP using a set of PCR experiments. Eleven IMP-27-producing Providencia rettgeri isolates were detected and tested for antimicrobial susceptibility, epidemiological and phylogenetic relatedness, transferability and genetic context of blaIMP-27 gene. P. rettgeri isolates showed resistant phenotype to cephalosporins and tetracycline and were assigned to two epidemiological unrelated clusters. Isolates from the first cluster originated from two different regions and they carried lnu(F) gene conferring resistance to lincosamides and a plasmid 40-60 kb in size. All isolates from the second cluster originated from the same location, harboured a 120 kb plasmid and no additional resistance determinants. The gene blaIMP-27 was located on the chromosome as a gene cassette of a class 2 integron. Although the prevalence of carbapenemase producers in this study was low, our results point out that wild birds are possible vectors of bacteria resistant to antibiotics of last resort

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    10606 - Microbiology

Result continuities

  • Project

    <a href="/en/project/LQ1601" target="_blank" >LQ1601: CEITEC 2020</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů