Immune reaction of Koi carp and Amur wild carp to Koi herpesvirus infection

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F21%3AN0000099" target="_blank" >RIV/00027162:_____/21:N0000099 - isvavai.cz</a>
Result on the web
<a href="https://fvhe.vfu.cz/files/upload/KMVP%202021_Sborník_1.pdf" target="_blank" >https://fvhe.vfu.cz/files/upload/KMVP%202021_Sborník_1.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Immune reaction of Koi carp and Amur wild carp to Koi herpesvirus infection
Original language description
Common carp is one of the most economically important freshwater fish in the world. Koi herpesvirus (KHV) causes serious disease affecting common carp and its breeds. In this study, we focused on revealing influence of immune reaction (IR) on diametrically different mortality between chosen breeds of common carp. We have chosen koi carp (koi), susceptible to KHV and its highly resistant wild variety Amur carp (AS) as model organisms. We measured levels of expression of selected genes related to antiviral IR, with focus on class I interferon (IFN-I) signalling. We detected overexpression of IFN-I gene in lymphatic organs of AS in early phase of infection. On the other hand, we observed increased expression of some IR related genes in later phase of infection in koi carp samples. Further, we found out in infected fish generally increased expression of mx gene co-inducing antiviral state in cell.
Czech name
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Czech description
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Project
<a href="/en/project/EF16_019%2F0000869" target="_blank" >EF16_019/0000869: Sustainable production of healthy fish in various aquaculture systems - PROFISH</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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