Effects of different pharmaceutical residues on embryos of fish species native to Central Europe

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F22%3AN0000006" target="_blank" >RIV/00027162:_____/22:N0000006 - isvavai.cz</a>
Alternative codes found
RIV/62156489:43210/22:43920569 RIV/62157124:16270/22:43880175
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0045653521033877" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0045653521033877</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.chemosphere.2021.132915" target="_blank" >10.1016/j.chemosphere.2021.132915</a>

Result language
angličtina
Original language name
Effects of different pharmaceutical residues on embryos of fish species native to Central Europe
Original language description
Concentrations of pharmacologically active substance residues are increasing dramatically throughout the world and are considered to be serious danger for the aquatic environment. Recent surveys have shown that these substances can cause negative effects to non-target organisms. High occurrence of residues in the aquatic environment is due to increasing prescription and consumption of drugs, discharge in wastewater and its imperfect purification in wastewater treatment plants. In the present study, we tested the effects of commonly used pharmacologically active substances such as antibiotics, analgesics and antidepressants, on embryonic stages of fish. In particular, concentration range of tramadol, enrofloxacine and nortriptylin was tested on zebrafish (Danio rerio; common toxicological model organism), common carp (Cyprinus carpio), catfish (Silurus glanis), and tench (Tinca tinca) ¬– species native to freshwaters of central Europe. Even though the effects on hatching, mortality and malformation occurence were observed only in the high tested concentrations, the results of the gene expression show, that even the low, environmentally relevant concentrations of pharmaceutical residue can cause signifficant changes in embryo early development.
Czech name
—
Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
40301 - Veterinary science

Project
<a href="/en/project/EF16_019%2F0000869" target="_blank" >EF16_019/0000869: Sustainable production of healthy fish in various aquaculture systems - PROFISH</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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