Gordonia species as a rare pathogen isolated from milk of dairy cows with mastitis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F22%3AN0000025" target="_blank" >RIV/00027162:_____/22:N0000025 - isvavai.cz</a>
Result on the web
<a href="https://www.nature.com/articles/s41598-022-09340-4" target="_blank" >https://www.nature.com/articles/s41598-022-09340-4</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41598-022-09340-4" target="_blank" >10.1038/s41598-022-09340-4</a>
Alternative languages
Result language
angličtina
Original language name
Gordonia species as a rare pathogen isolated from milk of dairy cows with mastitis
Original language description
While Gordonia species have long been known to cause severe inflammations in human medicine, the pathogenic effects of gordonias in veterinary medicine have rarely been described. Between 2010 and 2019, we collected microorganisms of the genus Gordonia isolated from milk samples from dairy cows with mastitis. We describe the growth properties of these microorganisms, their prevalence, virulence factors and susceptibility to antimicrobial agents. From 31,534 quarter milk samples processed by standard culture methods27 isolates of Gordonia species (0.086% prevalence) were identified by a molecular phenotyping method. The isolates originated from 17 farms in 12 districts of the Czech Republic. Twenty-one isolates were tested for susceptibility to 7 antimicrobials by the disc diffusion method. Notably, 100% of these isolates were susceptible to streptomycin and neomycin, 85.6% to tetracycline and cefovecin, 76.2% to penicillin G, 47.6% to trimethoprim/sulfamethoxazole and 0% to clindamycin. The species was determined to be Gordonia paraffinivorans by whole genome sequencing for 9 isolates (from 8 farms in 7 districts). These isolates showed the highest similarity to two reference strains from the environment. In all these isolates, we identified genes encoding virulence factors, which are very similar to the genes of virulence factors expressed in Mycobacterium tuberculosis and Mycobacterium smegmatis. However, genome analysis revealed 61 unique genes in all 9 sequenced isolates.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
40301 - Veterinary science
Result continuities
Project
<a href="/en/project/QK22020292" target="_blank" >QK22020292: Certification of dairy cattle farms according to the consumption of antimicrobials and mammary gland health to reduce their consumption, rationalize their use and reduce resistance to them</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Scientific Reports
ISSN
2045-2322
e-ISSN
2045-2322
Volume of the periodical
12
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
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UT code for WoS article
000781187500033
EID of the result in the Scopus database
2-s2.0-85128217931