The immune system of the ferret (Mustela putorius furo) – A review
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F22%3AN0000053" target="_blank" >RIV/00027162:_____/22:N0000053 - isvavai.cz</a>
Alternative codes found
RIV/62157124:16170/22:43880208
Result on the web
<a href="https://www.agriculturejournals.cz/web/vetmed.htm?type=article&id=22_2021-VETMED" target="_blank" >https://www.agriculturejournals.cz/web/vetmed.htm?type=article&id=22_2021-VETMED</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.17221/22/2021-VETMED" target="_blank" >10.17221/22/2021-VETMED</a>
Alternative languages
Result language
angličtina
Original language name
The immune system of the ferret (Mustela putorius furo) – A review
Original language description
The basic information dealing with the anatomy of the ferret’s immune system, cross-reactivity of the ferret leukocytes with polyclonal and monoclonal antibodies in vitro and immune response to the mitogens and various infections are presented. The leukocyte numbers in the peripheral blood in the ferrets are lower compared to other species and only one subclass of IgG has been identified in ferrets so far. Lymphocytes make up 12–67% of all the leukocytes in the peripheral blood of the healthy adult ferrets. Lymphocyte subpopulations are similar to other mammals and include T- and B-lymphocytes. T-lymphocytes differentiate into helper (Th) lymphocytes and cytotoxic (Tc) lymphocytes. Currently, ferret granulocytes (CD11), B-lymphocytes (CD79α), T-lymphocytes (CD3), Th-lymphocytes (CD3, CD4), Tc-lymphocytes (CD3, CD8), and CD30, CD45 subpopulations are detected with the use of a number of polyclonal as well as with monoclonal antibodies. In a lymphocyte transformation assay, the mitogen response of the peripheral blood mononuclear cells to concanavalin A (ConA), phytohaemagglutinin (PHA), and pokeweed mitogen (PWM) is the greatest at day 2, 2 and 3, respectively. Serious lymphopenia is observed in ferrets during a distemper infection. A significant decrease in the lymphocyte transformation activity is observed on day 5 and reaches a maximal decrease on days 8–11, with full recovery on days 23–30 after the inoculation of laboratory ferrets with the distemper virus. Ferrets have also been used in studies related to the function of the immune system in Helicobacter pylori infections, Crohn’s disease and bronchial asthma.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
40301 - Veterinary science
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Veterinární medicína
ISSN
0375-8427
e-ISSN
1805-9392
Volume of the periodical
67
Issue of the periodical within the volume
8
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
10
Pages from-to
408-417
UT code for WoS article
000809593600001
EID of the result in the Scopus database
2-s2.0-85132226176