Innate immune response of common Carp (Cyprinus carpio L.) to Koi herpesvirus infection
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F22%3AN0000135" target="_blank" >RIV/00027162:_____/22:N0000135 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Innate immune response of common Carp (Cyprinus carpio L.) to Koi herpesvirus infection
Original language description
Common carp is the most economically important fish in Czech Republic. However, a profit, earned by breeding of common carp, may be reduced by many diseases, among which viral diseases are the most serious matter. Koi herpesvirus (KHV) disease is probably the most serious viral disease affecting common carp. KHV disease affects only common carp, its strains and some hybrids of common carp and other cyprinids. KHV disease morbidity and mortality can reach one hundred percent, especially in juvenile individuals. Mortality rates of KHV disease could be significantly different among different strains of common carp. Further, KHV is able to kill diseased carp within one week after infection. Importance of KHV disease is even higher, because neither effective KHV treatment nor vaccine are available on the market in EU. The aim of presented study is to show current discoveries in innate immune response of common carp to KHV. Immune responses to KHV of two common carp breeds were compared: amur wild carp, which is highly resistant to KHV and Koi carp, which is susceptible to KHV. Analysis was focused on known antiviral immune response mechanisms, in particular class I interferon signalling, mechanism of complement cascade and cell-mediated cytotoxicity.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
40301 - Veterinary science
Result continuities
Project
<a href="/en/project/EF16_019%2F0000869" target="_blank" >EF16_019/0000869: Sustainable production of healthy fish in various aquaculture systems - PROFISH</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů