New directions in the experimental therapy of tick-borne encephalitis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F23%3AN0000013" target="_blank" >RIV/00027162:_____/23:N0000013 - isvavai.cz</a>
Alternative codes found
RIV/60077344:_____/23:00572867 RIV/00216224:14310/23:00130312
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S016635422200273X?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S016635422200273X?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.antiviral.2022.105504" target="_blank" >10.1016/j.antiviral.2022.105504</a>
Alternative languages
Result language
angličtina
Original language name
New directions in the experimental therapy of tick-borne encephalitis
Original language description
Tick-borne encephalitis (TBE) is a potentially fatal disease common in much of Europe and Asia. There is no specific therapy for the treatment of TBE patients. However, great efforts are being made to develop small molecules that specifically interfere with the TBE virus life cycle. In particular, recently various nucleoside analogues that can inhibit the viral replicase, such as the RNA-dependent RNA polymerase or viral methyltransferases, have been explored. In addition, promising human or chimeric monoclonal antibodies have been developed that could be used for postexposure prophylaxis or early therapy of TBE. This review summarizes the latest directions and experimental approaches that may be used to combat TBE in humans.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10607 - Virology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Antiviral Research
ISSN
0166-3542
e-ISSN
1872-9096
Volume of the periodical
210
Issue of the periodical within the volume
February 2023
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
6
Pages from-to
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UT code for WoS article
000997347600001
EID of the result in the Scopus database
2-s2.0-85146444105