New directions in the experimental therapy of tick-borne encephalitis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F23%3A00572867" target="_blank" >RIV/60077344:_____/23:00572867 - isvavai.cz</a>
Alternative codes found
RIV/00027162:_____/23:N0000013 RIV/00216224:14310/23:00130312
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S016635422200273X?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S016635422200273X?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.antiviral.2022.105504" target="_blank" >10.1016/j.antiviral.2022.105504</a>
Alternative languages
Result language
angličtina
Original language name
New directions in the experimental therapy of tick-borne encephalitis
Original language description
Tick-borne encephalitis (TBE) is a potentially fatal disease common in much of Europe and Asia. There is no specific therapy for the treatment of TBE patients. However, several efforts are being made to develop small molecules that specifically interfere with the life cycle of TBE virus. In particular, recently various nucleoside analogues that can inhibit the viral replicase, such as the RNA-dependent RNA polymerase or viral methyl-transferases, have been explored. In addition, human or chimeric (i.e., structural chimeras that combine mouse variable domains with human constant domains) monoclonal antibodies with promising potential for postexposure prophylaxis or early therapy have been developed. This review summarizes the latest directions and experimental approaches that may be used to combat TBE in humans.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30102 - Immunology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Antiviral Research
ISSN
0166-3542
e-ISSN
1872-9096
Volume of the periodical
210
Issue of the periodical within the volume
JAN
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
3
Pages from-to
105504
UT code for WoS article
000997347600001
EID of the result in the Scopus database
2-s2.0-85146444105