Chromosomal damage in occupationally exposed health professionals assessed by two cytogenetic methods
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F23%3AN0000018" target="_blank" >RIV/00027162:_____/23:N0000018 - isvavai.cz</a>
Alternative codes found
RIV/00209805:_____/23:00079056
Result on the web
<a href="https://www.tandfonline.com/doi/full/10.1080/19338244.2022.2118213" target="_blank" >https://www.tandfonline.com/doi/full/10.1080/19338244.2022.2118213</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/19338244.2022.2118213" target="_blank" >10.1080/19338244.2022.2118213</a>
Alternative languages
Result language
angličtina
Original language name
Chromosomal damage in occupationally exposed health professionals assessed by two cytogenetic methods
Original language description
Abstract: The study assessed occupationally induced chromosomal damage in hospital personnel at risk of exposure to antineoplastic drugs and/or low doses of ionizing radiation by two cytogenetic methods. Cultured peripheral blood lymphocytes of eighty-five hospital workers were examined twice over 2 to 3 years by classical chromosomal aberration analysis and fluorescence in situ hybridization. The comparison of the 1st and the 2nd sampling of hospital workers showed a significant increase in chromatid and chromosomal aberrations (all p < 0.05) examined by classical chromosomal aberration analysis, and in unstable aberrations (all p < 0.05) detected by fluorescence in situ hybridization. Both cytogenetic methods were able to detect an increase of unstable aberrations in the 2nd sampling. The raised frequency of unstable cytogenetic parameters suggested higher recent exposure to genotoxic agents.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30305 - Occupational health
Result continuities
Project
<a href="/en/project/NV15-33968A" target="_blank" >NV15-33968A: The application of modern molecular genetic methods for the determination of genotoxic changes in at-risk populations</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Archives of Environmental & Occupational Health
ISSN
1933-8244
e-ISSN
2154-4700
Volume of the periodical
78
Issue of the periodical within the volume
3
Country of publishing house
GB - UNITED KINGDOM
Number of pages
12
Pages from-to
158-169
UT code for WoS article
000851597800001
EID of the result in the Scopus database
2-s2.0-85138315930