Immune response in diseased and healthy common carp exposed to carp edema virus

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F24%3AN0000091" target="_blank" >RIV/00027162:_____/24:N0000091 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/24:00138938 RIV/62156489:43210/24:43925635 RIV/62157124:16270/24:43881460
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/10.1111/jfd.14012" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1111/jfd.14012</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/jfd.14012" target="_blank" >10.1111/jfd.14012</a>

Result language
angličtina
Original language name
Immune response in diseased and healthy common carp exposed to carp edema virus
Original language description
Common carp is one of the most economically valuable freshwater fish worldwide and its aquaculture can be severely affected by the carp edema virus disease (CEVD). The current study is based on a natural outbreak of CEVD with both clinically healthy and diseased fish of various origin, simultaneously present in one pond and exposed to the virus. The mRNA expression of genes to be associated with the known antiviral immune mechanisms such as type I interferon signalling and cell-mediated cytotoxicity was detected and quantified. Furthermore, complete protein expression profile was used for description of differences between these groups in various tissues. Significant differences in expression profiles of common carp with and without clinical signs were strongly dependent on the organ from which the sample originated. The complement cascade components such as various C3 proteins were upregulated only in the less affected tissues of head kidney and spleen. Other complement proteins such as B/C2 and C9 were upregulated in kidney, spleen and gills, but not in skin. On the other hand, lysozymes C and G, were observed upregulated in the most affected tissues of skin and gills.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
40301 - Veterinary science

Project
<a href="/en/project/EF16_019%2F0000869" target="_blank" >EF16_019/0000869: Sustainable production of healthy fish in various aquaculture systems - PROFISH</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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