Comparative Genome Analysis and Characterization of the Probiotic Properties of Lactic Acid Bacteria Isolated from the Gastrointestinal Tract of Wild Boars in the Czech Republic
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F25%3AN0000071" target="_blank" >RIV/00027162:_____/25:N0000071 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/25:00140264
Result on the web
<a href="https://link.springer.com/article/10.1007/s12602-024-10259-7" target="_blank" >https://link.springer.com/article/10.1007/s12602-024-10259-7</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s12602-024-10259-7" target="_blank" >10.1007/s12602-024-10259-7</a>
Alternative languages
Result language
angličtina
Original language name
Comparative Genome Analysis and Characterization of the Probiotic Properties of Lactic Acid Bacteria Isolated from the Gastrointestinal Tract of Wild Boars in the Czech Republic
Original language description
Probiotics are important components for maintaining a healthy gut microbiota in pigs, especially in post-weaned piglets. Lactic acid bacteria derived from the gastrointestinal tract of wild boars can serve as a source of beneficial probiotic strains with suitable properties for use in pig husbandry. In the study, we analyzed and characterized 15 strains of Limosilactobacillus mucosae obtained from the gut contents of wild boars to assess their safety and beneficial properties as probiotic candidates. The strains were compared using pan genomic analysis with 49 L. mucosae strains obtained from the NCBI database. All isolated strains demonstrated safety by absence of transferrable antimicrobial resistance genes and hemolysin activity. Based on the presence of beneficial genes, five candidates with probiotic properties were selected and subjected to phenotypic profiling. Five selected isolates exhibited the ability to survive conditions mimicking passage through the host’s digestive tract, such as low pH and the presence of bile salts. Furthermore, five selected strains demonstrated the presence of multiple carbohydrate-active enzymes and the ability to utilize various carbohydrate substrates. These strains can enhance the digestibility of oligo- or polysaccharide substrates found in food or feed, specifically resistant starch, α-galactosides, cellobiose, gentiobiose, and arabinoxylans. Based on the results obtained, the L. mucosae isolates tested in the study appear to be promising candidates for use as probiotics in pigs.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
40301 - Veterinary science
Result continuities
Project
<a href="/en/project/QK1910351" target="_blank" >QK1910351: Wild boar and domestic pigs as a source of probiotic cultures and the influence of technological processes of preparation and synbiotic feed composition on its effectiveness and functionality</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Probiotics and Antimicrobial Proteins
ISSN
1867-1306
e-ISSN
1867-1314
Volume of the periodical
17
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
19
Pages from-to
1820-1838
UT code for WoS article
001207122200002
EID of the result in the Scopus database
2-s2.0-85191091250