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Chickens as a model for host-gut microbiota studies

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F25%3AN0000124" target="_blank" >RIV/00027162:_____/25:N0000124 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Chickens as a model for host-gut microbiota studies

  • Original language description

    15th Host Pathogen Interaction Forum 2025, 10-13 October 2025. Třešť, Česká republika. Around 240 million chickens are hatched annually in the Czech Republic what corresponds to approx. 1 million chickens produced every working day. This makes this animal simply available and high production also reduces cost of a single chick. Moreover, since chicks are hatched in hatcheries without any contact with parents, millions of chicks are available every week and these might be colonised with microbiota of various composition. Although ignoring some facts which are influenced by raising of chicks in the absence of adult birds may lead to confounding conclusions on development of chicken gut microbiota, once correctly understood, there is no longer better animal model than chicken. Newly hatched chicks can be oral inoculated with faecal material from adult hens and microbiota increasing chicken resistance can be selected. If the selection is modified towards body weight increase, microbiota positively affecting growth can be identified. Following administration of faecal material, microbiota colonising gut lumen and gut mucosal surfaces can be defined. It is also possible to have an access to chicks 1, 2, 3 or 4 days of age and define fine development of gut microbiota before and after beginning of feed income. Finally, not only bacteria but also phages specific against particular bacterial species can be easily tested in chickens.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    40301 - Veterinary science

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2025

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů