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Increased oxidative/nitrosative stress markers measured non- invasively in patients with high 2,3,7,8-tetrachloro-dibenzo-p-dioxin plasma level

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F11%3A10435" target="_blank" >RIV/00064165:_____/11:10435 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/11:10435 RIV/60461373:22310/11:43892513 RIV/61388971:_____/11:00377562 RIV/61388955:_____/11:00377562

  • Result on the web

    <a href="http://node.nel.edu/?node_id=12147" target="_blank" >http://node.nel.edu/?node_id=12147</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Increased oxidative/nitrosative stress markers measured non- invasively in patients with high 2,3,7,8-tetrachloro-dibenzo-p-dioxin plasma level

  • Original language description

    The aim was to investigate markers of oxidative/nitrosative stress and onflammation using noninvasive methods in subjects who got ill due to severe occupational exposure to TCDD in the years 1965-1968. Mean TCDD plasma level in 2010 was 175+-162 lipids,total TCDD content in the body 5,16+-4,62 microg. Reduction of cerebral blood flow in SPECT progressed in 8 patients, finding was stable in 2 subjects, and improvement occured in 1 patients. In the EBC, 10 from 12 markers were significantly increased inthe patients (p=0,05). In the urine, 7 markers were significantly higher than in the controls (p=0,05): 8-isoprostane, MDA, HNE, LTC4, LTE4, o-Tyr and NO-Tyr. In the plasma, only NO-Tyr and 8_OHG were elevated(p=0,05).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FE - Other fields of internal medicine

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NS10298" target="_blank" >NS10298: Monitoring of biorhythms of metabolites arachidonic acid by standardized methodology</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Neuroendocrinology Letters

  • ISSN

    0172-780X

  • e-ISSN

  • Volume of the periodical

    32

  • Issue of the periodical within the volume

  • Country of publishing house

    SE - SWEDEN

  • Number of pages

    6

  • Pages from-to

    71-76

  • UT code for WoS article

    000300544100009

  • EID of the result in the Scopus database