Tests of manual dexterity and speed in Parkinson's disease: Not all measure the same

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F16%3A10325024" target="_blank" >RIV/00064165:_____/16:10325024 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/16:10325024 RIV/00216208:11130/16:10325024 RIV/68407700:21460/16:00243371 RIV/00064203:_____/16:10325024

Result on the web

<a href="http://dx.doi.org/10.1016/j.parkreldis.2016.05.009" target="_blank" >http://dx.doi.org/10.1016/j.parkreldis.2016.05.009</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.parkreldis.2016.05.009" target="_blank" >10.1016/j.parkreldis.2016.05.009</a>

Result language

angličtina

Original language name

Tests of manual dexterity and speed in Parkinson's disease: Not all measure the same

Original language description

Introduction: Timed performance tests were introduced to overcome the disadvantages of subjective evaluation of bradykinesia in Parkinson's disease (PD). We aimed to verify their discriminative properties and compare them with the motion capture analysis of finger tapping. Methods: We included 22 PD patients (10 M, 12 F), mean age 64 (range 48-82) yrs, Hoehn & Yahr stage 2 (1-2.5) and 22 (10 M, 12 F) normal controls, mean age 66 (41-82) yrs. The key tapping subtest of the Halstead-Reitan battery, the Purdue Pegboard test, and the Bradykinesia-Akinesia Incoordination (BRAIN) test were performed according to the test manuals. The finger tapping subtest of the UPDRS-III, item 23 was recorded using a contactless 3D motion capture system Optitrack-V120. Average frequency (AvgFrq), maximum opening velocity (MaxOpV) and amplitude decrement (AmpDec) were computed and simultaneous video recordings of finger tapping were rated by two experts. Results: The AmpDec and MaxOpV motion capture measures best differentiated between PD patients and controls (AUC = 0.87 and 0.81). Of the instrumental tests, only the Purdue Pegboard attained significance in differentiating PD patients from controls (AUC = 0.80). In PD patients, MaxOpV correlated with the finger tapping ratings and BRAIN test, and AvgFrq correlated with the BRAIN and Halstead-Reitan test scores. Moreover, correlations were found between the Purdue Pegboard and finger tapping ratings. Conclusions: Contactless 3D motion capture of finger tapping allowed an independent analysis of individual components of bradykinesia, demonstrating the amplitude decrement and maximum opening velocity as the most powerful discriminators between PD patients and controls.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

—

Project

<a href="/en/project/NT14181" target="_blank" >NT14181: Analysis of bradykinesia and speech in Parkinson’s disease</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Parkinsonism and Related Disorders

ISSN

1353-8020

e-ISSN

—

Volume of the periodical

28

Issue of the periodical within the volume

Jul

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

118-123

UT code for WoS article

000379705500019

EID of the result in the Scopus database

2-s2.0-84966658565