Premature infants born at <25 weeks of gestation may be compromised by currently recommended resuscitation techniques
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F16%3A10325269" target="_blank" >RIV/00064165:_____/16:10325269 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/16:10325269
Result on the web
<a href="http://onlinelibrary.wiley.com/doi/10.1111/apa.13178/epdf" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/apa.13178/epdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/apa.13178" target="_blank" >10.1111/apa.13178</a>
Alternative languages
Result language
angličtina
Original language name
Premature infants born at <25 weeks of gestation may be compromised by currently recommended resuscitation techniques
Original language description
AimStandard resuscitation guidelines are based on data from a range of gestational ages. We sought to evaluate the effectiveness of our delivery room resuscitation protocol across a range of gestational ages in preterm infants born at <29weeks. MethodsWe performed an observational study of prospectively collected video recordings of 73 preterm infants. The percentage of bradycardic patients, time to reach target oxygen saturation and the extent of all interventions were compared between three gestational age groups: 22-24weeks (n=22), 25-26weeks (n=27) and 27-28weeks (n=24). ResultsAlthough the same resuscitation protocol was followed for all infants, bradycardic infants born <25weeks responded poorly and required significantly longer to reach oxygen saturation targets of >70%, >80% and >90% (p<0.03). They required significantly more interventions and had higher rate of death (p<0.05) and severe intraventricular haemorrhage (p<0.03). Significantly lower heart rate and oxygen saturation values were found in infants with intraventricular haemorrhage. ConclusionCurrent recommendations for resuscitation may fail to achieve timely lung aeration in infants born at the borderline of viability, leading to higher mortality and morbidity. Sustained inflation and delayed cord clamping may be effective alternatives.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FK - Gynaecology and obstetrics
OECD FORD branch
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Result continuities
Project
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Continuities
O - Projekt operacniho programu
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Acta Paediatrica
ISSN
0803-5253
e-ISSN
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Volume of the periodical
105
Issue of the periodical within the volume
4
Country of publishing house
GB - UNITED KINGDOM
Number of pages
9
Pages from-to
"E142"-"E150"
UT code for WoS article
000371892200001
EID of the result in the Scopus database
2-s2.0-84949267433