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Premature infants born at <25 weeks of gestation may be compromised by currently recommended resuscitation techniques

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F16%3A10325269" target="_blank" >RIV/00064165:_____/16:10325269 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/16:10325269

  • Result on the web

    <a href="http://onlinelibrary.wiley.com/doi/10.1111/apa.13178/epdf" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/apa.13178/epdf</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1111/apa.13178" target="_blank" >10.1111/apa.13178</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Premature infants born at <25 weeks of gestation may be compromised by currently recommended resuscitation techniques

  • Original language description

    AimStandard resuscitation guidelines are based on data from a range of gestational ages. We sought to evaluate the effectiveness of our delivery room resuscitation protocol across a range of gestational ages in preterm infants born at <29weeks. MethodsWe performed an observational study of prospectively collected video recordings of 73 preterm infants. The percentage of bradycardic patients, time to reach target oxygen saturation and the extent of all interventions were compared between three gestational age groups: 22-24weeks (n=22), 25-26weeks (n=27) and 27-28weeks (n=24). ResultsAlthough the same resuscitation protocol was followed for all infants, bradycardic infants born <25weeks responded poorly and required significantly longer to reach oxygen saturation targets of >70%, >80% and >90% (p<0.03). They required significantly more interventions and had higher rate of death (p<0.05) and severe intraventricular haemorrhage (p<0.03). Significantly lower heart rate and oxygen saturation values were found in infants with intraventricular haemorrhage. ConclusionCurrent recommendations for resuscitation may fail to achieve timely lung aeration in infants born at the borderline of viability, leading to higher mortality and morbidity. Sustained inflation and delayed cord clamping may be effective alternatives.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FK - Gynaecology and obstetrics

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    O - Projekt operacniho programu

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Acta Paediatrica

  • ISSN

    0803-5253

  • e-ISSN

  • Volume of the periodical

    105

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    9

  • Pages from-to

    "E142"-"E150"

  • UT code for WoS article

    000371892200001

  • EID of the result in the Scopus database

    2-s2.0-84949267433