Comparison of MicroRNA Content in Plasma and Urine Indicates the Existence of a Transrenal Passage of Selected MicroRNAs
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F16%3A10327076" target="_blank" >RIV/00064165:_____/16:10327076 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/16:10327076 RIV/00064203:_____/16:10327076 RIV/00216208:11110/16:10327076
Result on the web
<a href="http://dx.doi.org/10.1007/978-3-319-42044-8_18" target="_blank" >http://dx.doi.org/10.1007/978-3-319-42044-8_18</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-319-42044-8_18" target="_blank" >10.1007/978-3-319-42044-8_18</a>
Alternative languages
Result language
angličtina
Original language name
Comparison of MicroRNA Content in Plasma and Urine Indicates the Existence of a Transrenal Passage of Selected MicroRNAs
Original language description
MicroRNAs (miRNAs) in urine are examined as potential biomarkers. We examined the urine samples from 70 individuals (45 males, 25 females, mean age 65 years, range 20-84 years). Of the urine donors, 15 were healthy volunteers, 5 were patients with non-cancer diseases, 50 were patients with different stages of bladder cancer. To examine the spectrum of miRNAs in the cell-free fraction of urine, TaqMan Human miRNA Array Card A v.2.1 was used. A set of 30 miRNAs were found that are constantly present in urine supernatants independently of sex, age and health status of the subjects. We compared this set with miRNAs found in plasma, expressed in kidney and genito-urinary tract. Our results indicate that some miRNA could be transferred from the circulation into urine.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT12417" target="_blank" >NT12417: Prospects of MicroRNA, mRNA and FreeDNA for Early Non-invasive Detection and Prognosis Assessment in Urinary Bladder Cancer Patients</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Advances in Experimental Medicine and Biology
ISSN
0065-2598
e-ISSN
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Volume of the periodical
924
Issue of the periodical within the volume
October
Country of publishing house
US - UNITED STATES
Number of pages
4
Pages from-to
97-100
UT code for WoS article
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EID of the result in the Scopus database
2-s2.0-84996551493