Isolated low initial differential renal function in patients with primary non-refluxing megaureter should not be considered an indication for early surgery: A multicentric study

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F16%3A10328353" target="_blank" >RIV/00064165:_____/16:10328353 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/16:00092513 RIV/00216208:11110/16:10328353 RIV/00216208:11510/16:10328353 RIV/61989592:15110/16:33162243 and 2 more
Result on the web
<a href="http://dx.doi.org/10.1016/j.jpurol.2016.05.025" target="_blank" >http://dx.doi.org/10.1016/j.jpurol.2016.05.025</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jpurol.2016.05.025" target="_blank" >10.1016/j.jpurol.2016.05.025</a>

Result language
angličtina
Original language name
Isolated low initial differential renal function in patients with primary non-refluxing megaureter should not be considered an indication for early surgery: A multicentric study
Original language description
Introduction: Low initial differential renal function (DRF) in patients with primary non-refluxing megaureter (PNRM) is considered an indication for surgery as are an increase of dilatation and symptoms. Objective: We hypothesized that low DRF is not necessarily a result of obstruction, but may be due to impaired development of the upper urinary tract. Thus, in the absence of symptoms, there is a low risk for further loss of renal function. This study aimed to assess whether initially low DRF is a reliable indicator of obstruction. Study design: We reviewed data from four university centers between 1995 and 2010. Patients under 12 months of age with unilateral primary non-refluxing megaureter (PNMR) and a DRF between 10% and 40%, and followed minimally 24 months, were included. Patients were placed in two groups based on management: group A, surgical; group B, conservative. The dynamics of DRF in relation to age and type of treatment was studied. In each patient we recorded the earliest (initial) DRF, the last known (final) DRF, the age when MAG-3 scans were performed and the type of treatment.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FJ - Surgery including transplantology
OECD FORD branch
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Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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