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Detection and identification of engineered nanoparticles in exhaled breath condensate, blood serum, and urine of occupationally exposed subjects

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F19%3A10396947" target="_blank" >RIV/00064165:_____/19:10396947 - isvavai.cz</a>

  • Alternative codes found

    RIV/68081715:_____/19:00503207 RIV/67985858:_____/19:00503207 RIV/61388955:_____/19:00503207 RIV/00216208:11110/19:10396947 and 3 more

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=-x_G4_GsSX" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=-x_G4_GsSX</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s00706-019-2379-z" target="_blank" >10.1007/s00706-019-2379-z</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Detection and identification of engineered nanoparticles in exhaled breath condensate, blood serum, and urine of occupationally exposed subjects

  • Original language description

    The use of nanotechnology and the fields of application of nanomaterials are growing vastly, but the negative health effects on the exposed employees are not well studied. The standardized methods of monitoring of occupational exposure are still absent. The task of occupational physicians is to find the ways of evaluation of potential risks of exposure to engineered nanoparticles and to determine the biomarkers for early diagnostics and prevention of occupational diseases. The aim of our study was to detect and identify engineered nanoparticles in biological samples received from occupationally exposed subjects and to evaluate the association of findings with the results of external aerosol measurements on the workplace. The study cohort consisted of two groups of subjects. The first group was exposed to engineered nanoparticles containing mainly iron, manganese, and carbon compounds; the second group was exposed to the nanoparticles containing copper oxide. The post-shift biological samples (urine, blood serum, and exhaled breath condensate) were collected. The analysis was performed by transmission electron microscopy and energy-dispersive spectroscopy. The nanoparticles were detected in all the biological samples. The most common identified chemical elements were the biogenic ones (carbon, potassium, chlorine, oxygen), but the nanoparticles containing metals were identified in EBC, blood, and urine as well (gold, silver, copper, lanthanum, cerium, and tantalum). Our results demonstrate the possibility of detection of occupational exposure to the engineered nanoparticles in human biological fluids. Further studies are necessary to compare the pre-shift and post-shift burden of samples with engineered nanoparticles and to determine the magnitude of occupational exposure during the shift. [GRAPHICS] .

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30304 - Public and environmental health

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Monatshefte für Chemie - Chemical Monthly

  • ISSN

    0026-9247

  • e-ISSN

  • Volume of the periodical

    150

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    AT - AUSTRIA

  • Number of pages

    13

  • Pages from-to

    511-523

  • UT code for WoS article

    000461394400018

  • EID of the result in the Scopus database

    2-s2.0-85061075454