Pressure and flow properties of cannulae for extracorporeal membrane oxygenation I: return (arterial) cannulae

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F19%3A10397705" target="_blank" >RIV/00064165:_____/19:10397705 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/19:10397705

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=PcMjc1J5rP" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=PcMjc1J5rP</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1177/0267659119830521" target="_blank" >10.1177/0267659119830521</a>

Result language

angličtina

Original language name

Pressure and flow properties of cannulae for extracorporeal membrane oxygenation I: return (arterial) cannulae

Original language description

Adequate extracorporeal membrane oxygenation support in the adult requires cannulae permitting blood flows up to 6-8 L/minute. In accordance with Poiseuille&apos;s law, flow is proportional to the fourth power of cannula inner diameter and inversely proportional to its length. Poiseuille&apos;s law can be applied to obtain the pressure drop of an incompressible, Newtonian fluid (such as water) flowing in a cylindrical tube. However, as blood is a pseudoplastic non-Newtonian fluid, the validity of Poiseuille&apos;s law is questionable for prediction of cannula properties in clinical practice. Pressure-flow charts with non-Newtonian fluids, such as blood, are typically not provided by the manufacturers. A standardized laboratory test of return (arterial) cannulae for extracorporeal membrane oxygenation was performed. The aim was to determine pressure-flow data with human whole blood in addition to manufacturers&apos; water tests to facilitate an appropriate choice of cannula for the desired flow range. In total, 14 cannulae from three manufacturers were tested. Data concerning design, characteristics, and performance were graphically presented for each tested cannula. Measured blood flows were in most cases 3-21% lower than those provided by manufacturers. This was most pronounced in the narrow cannulae (15-17 Fr) where the reduction ranged from 27% to 40% at low flows and 5-15% in the upper flow range. These differences were less apparent with increasing cannula diameter. There was a marked disparity between manufacturers. Based on the measured results, testing of cannulae including whole blood flows in a standardized bench test would be recommended.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Perfusion

ISSN

0267-6591

e-ISSN

—

Volume of the periodical

34

Issue of the periodical within the volume

Suplement 1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

58-64

UT code for WoS article

000464422000008

EID of the result in the Scopus database

2-s2.0-85064316040