Leukocyte telomere length is not affected by long-term occupational exposure to nano metal oxides

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F19%3A10401966" target="_blank" >RIV/00064165:_____/19:10401966 - isvavai.cz</a>
Alternative codes found
RIV/68081715:_____/19:00517643 RIV/67985858:_____/19:00517643 RIV/00216208:11110/19:10401966 RIV/00023001:_____/19:00078660 RIV/46747885:24210/19:00008853
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=8h9078YRnK" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=8h9078YRnK</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2486/indhealth.2018-0146" target="_blank" >10.2486/indhealth.2018-0146</a>

Result language
angličtina
Original language name
Leukocyte telomere length is not affected by long-term occupational exposure to nano metal oxides
Original language description
The aim of this study was to ascertain whether long-term occupational exposure to nanoparticles would affect relative leukocyte telomere length (LrTL). We analysed occupational exposure to size-resolved aerosol particles, with special emphasis on nanoparticles at two workshops: i/ the production of nanocomposites containing metal oxides; ii/ laboratory to test experimental exposure of nano-CuO to rodents. Thirty five exposed researchers (age 39.5 +/- 12.6 yr; exposure duration 6.0 +/- 3.7 yr) and 43 controls (40.4 +/- 10.5 yr) were examined. LrTL did not significantly (p=0.14) differ between the exposed researchers (0.92 +/- 0.13) and controls (0.86 +/- 0.15). In addition, no significant correlation (r=-0.22, p=0.22) was detected between the duration of occupational exposure and LrTL. The results remained non-significant after multiple adjustments for age, sex and smoking status. Our pilot results suggest that relative leukocyte telomere length is not affected by occupational exposure to nanoparticles.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30304 - Public and environmental health

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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