The role of cholesterol metabolism in multiple sclerosis: From molecular pathophysiology to radiological and clinical disease activity
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F22%3A10444171" target="_blank" >RIV/00064165:_____/22:10444171 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/22:10444171
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=rz0yKibK8_" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=rz0yKibK8_</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.autrev.2022.103088" target="_blank" >10.1016/j.autrev.2022.103088</a>
Alternative languages
Result language
angličtina
Original language name
The role of cholesterol metabolism in multiple sclerosis: From molecular pathophysiology to radiological and clinical disease activity
Original language description
Multiple sclerosis (MS) is a chronic inflammatory disease of the CNS leading to demyelination and axonal degeneration. An increasing body of evidence suggests that lipid metabolism is associated with adverse clinical and MRI outcomes in MS. In this review we summarize the findings of association between low-density lipoproteins (LDL), high-density lipoproteins (HDL), their apolipoproteins and oxysterols with clinical and radiological disease activity in MS. Although the causality between disease activity in MS and abnormalities in lipid metabolism has not yet been elucidated, we suggest that advances in this field of research have the potential to improve understanding of MS pathophysiology and the identification of new treatment targets and strategies.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
<a href="/en/project/NV18-08-00062" target="_blank" >NV18-08-00062: Quantitative multiparametric MRI for longitudinal monitoring of multiple sclerosis: correlation with clinical status and biochemical markers</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Autoimmunity Reviews
ISSN
1568-9972
e-ISSN
1873-0183
Volume of the periodical
21
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
6
Pages from-to
103088
UT code for WoS article
000793724700006
EID of the result in the Scopus database
2-s2.0-85127757594