Semi-automatic quantification of mosaic perfusion of lung parenchyma and its correlation with haemodynamic parameters in patients with chronic thromboembolic pulmonary hypertension

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F23%3A10472577" target="_blank" >RIV/00064165:_____/23:10472577 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/23:10472577 RIV/44555601:13450/23:43899124

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=INuRzKu6Q2" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=INuRzKu6Q2</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.crad.2023.08.008" target="_blank" >10.1016/j.crad.2023.08.008</a>

Result language

angličtina

Original language name

Semi-automatic quantification of mosaic perfusion of lung parenchyma and its correlation with haemodynamic parameters in patients with chronic thromboembolic pulmonary hypertension

Original language description

AIM: To investigate the feasibility of semiautomatic quantification of mosaic perfusion and the associations between mosaic perfusion on computed tomography (CT; the ratio of hypo-perfused parenchyma to the whole lung volume) and haemodynamic parameters through linear regression analysis.MATERIALS AND METHODS: Fifty-eight consecutive patients (mean age 66 years, 28 fe -males) diagnosed with chronic thromboembolic pulmonary hypertension (CTEPH) in General University Hospital, Prague, in 2021 were evaluated retrospectively and underwent both right heart catheterisation and CT pulmonary angiography. The parameters derived from the CT examinations were correlated with the recorded haemodynamic parameters.RESULTS: A method was developed for semiautomatic detection of hypoperfused tissue from CT using widely available software and a statistically significant correlation was found between the proportion of hypoperfused parenchyma and the mean pulmonary artery pressure (mPAP; R-2 0.22; p&lt;0.01) and pulmonary vascular resistance (PVR; R-2 0.09; p&lt;0.05).CONCLUSIONS: The developed method facilitates the quantification of mosaic perfusion, which is associated with important haemodynamic parameters (mPAP and PVR) in patients with CTEPH.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30224 - Radiology, nuclear medicine and medical imaging

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Clinical Radiology

ISSN

0009-9260

e-ISSN

1365-229X

Volume of the periodical

78

Issue of the periodical within the volume

12

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

"e918"-"e924"

UT code for WoS article

001109603700001

EID of the result in the Scopus database

2-s2.0-85169509159