Unravelling head tremor mechanisms: insights from speech analysis in essential tremor and cervical dystonia

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F25%3A10499908" target="_blank" >RIV/00064165:_____/25:10499908 - isvavai.cz</a>

Alternative codes found

RIV/68407700:21230/25:00385049 RIV/68407700:21460/25:00385049 RIV/00216208:11110/25:10499908

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=KHpbn9MHtS" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=KHpbn9MHtS</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00702-025-02965-5" target="_blank" >10.1007/s00702-025-02965-5</a>

Result language

angličtina

Original language name

Unravelling head tremor mechanisms: insights from speech analysis in essential tremor and cervical dystonia

Original language description

Head tremor is a common symptom in both essential tremor (ET) and cervical dystonia (CD). Distinguishing between these two conditions can be challenging in clinical practice, particularly when head tremor is the dominant feature. Our goal was to explore the potential of speech assessment in recognizing the mechanisms of head tremor in patients with ET and CD. Objective acoustic vocal assessments of oral diadochokinesis, phonatory stability, vocal tremor, and speech timing were performed. Of the 93 patients assessed, 39 had cervical dystonia (CD) with head tremor, 38 had ET with head tremor (ET-HT), and 16 had ET with no head tremor (ET-nHT). Compared to both CD and ET-nHT, ET-HT showed irregular sequential motion rate, excessive pitch fluctuations, increased noise, and higher extent of vocal vibrato. Compared to CD, ET-HT also demonstrated slower sequential motion rate, prolonged pauses, and a slower articulation rate. Additionally, ET-HT had more pronounced vocal tremolo compared to ET-nHT. Speech assessment provided discrimination between the CD and ET-HT groups with an area under curve of 0.80. This study underscores the promising potential of speech analysis in recognizing mechanisms of head tremor in patients with ET or CD, revealing more severe and distinct speech impairments in ET-HT patients compared to those with CD.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

<a href="/en/project/LX22NPO5107" target="_blank" >LX22NPO5107: National institute for Neurological Research</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Neural Transmission

ISSN

0300-9564

e-ISSN

1435-1463

Volume of the periodical

132

Issue of the periodical within the volume

8

Country of publishing house

AT - AUSTRIA

Number of pages

8

Pages from-to

1171-1178

UT code for WoS article

001503450400001

EID of the result in the Scopus database

2-s2.0-105007682682