Obstructive sleep apnea as a possible mediator for the association between glymphatic function and body mass index in Parkinson's disease
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F25%3A10500711" target="_blank" >RIV/00064165:_____/25:10500711 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/25:10500711
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=wP5D_ib-po" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=wP5D_ib-po</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.21037/qims-2025-1124" target="_blank" >10.21037/qims-2025-1124</a>
Alternative languages
Result language
angličtina
Original language name
Obstructive sleep apnea as a possible mediator for the association between glymphatic function and body mass index in Parkinson's disease
Original language description
We have read with interest a recent paper by Tian et al., which investigated the impact of body mass index (BMI) on the glymphatic system function in patients with Parkinson's disease (PD). The authors used the diffusion tensor imaging analysis along the perivascular space (DTI-ALPS) method to obtain the ALPS index as a proxy for glymphatic system activity. They found that PD patients with higher BMI exhibited a reduced ALPS index, and the ALPS index in patients with obesity was statistically significantly lower than that in patients with normal weight. Furthermore, a significant negative correlation between the ALPS index and BMI was found among the PD patients in the study. In this letter, we aim to broaden the discussion by proposing the potential role of obstructive sleep apnea (OSA) as a mediator in the relationship between glymphatic function and BMI.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
—
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Quantitative Imaging in Medicine and Surgery
ISSN
2223-4292
e-ISSN
2223-4306
Volume of the periodical
15
Issue of the periodical within the volume
8
Country of publishing house
HK - HONG KONG
Number of pages
2
Pages from-to
7674-7675
UT code for WoS article
001547699500041
EID of the result in the Scopus database
2-s2.0-105013491295