Blood pressure levels are higher in individuals with type 1 diabetes mellitus compared to healthy subjects during exercise stress test
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F25%3A10500888" target="_blank" >RIV/00064165:_____/25:10500888 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/25:10500888
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=H1SWsou3_K" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=H1SWsou3_K</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41598-025-15513-8" target="_blank" >10.1038/s41598-025-15513-8</a>
Alternative languages
Result language
angličtina
Original language name
Blood pressure levels are higher in individuals with type 1 diabetes mellitus compared to healthy subjects during exercise stress test
Original language description
Type 1 diabetes mellitus (T1DM) is a chronic disease that usually manifests at a younger age and is associated with higher morbidity and mortality compared to the general population. The objective of this study was to assess the blood pressure response to exercise in patients with T1DM with varying durations of diabetes and with respect to the determinants of systolic blood pressure (SBP) and diastolic blood pressure (DBP) during the exercise stress test. This cross-sectional exploratory study included 52 patients (35 with T1DM aged < 35 years and 17 aged > 35 years) and 25 control subjects. All participants were untrained and underwent a cardiopulmonary exercise stress test using a cycle ergometer and their BP was measured manually. Compared to control subjects, both younger and older patients with T1DM had higher SBP and DBP at submaximal exercise load 0,5 W/kg (SBP 124 +/- 18; 142 +/- 17; 146 +/- 19 mmHg, p = 0.0004, respectively, and DBP 75 +/- 10; 84 +/- 7; 82 +/- 7 mmHg, p = 0.0015, respectively), and at peak exercise (SBP 170 +/- 24; 188 +/- 26; 192 +/- 23 mmHg, p = 0.0006, respectively. BP during exercise in T1DM patients in multivariate model was influenced by resting SBP, and diabetes duration. Patients with T1DM exhibited impaired BP control during exercise, which may serve as an early marker of heightened cardiovascular risk.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30202 - Endocrinology and metabolism (including diabetes, hormones)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Scientific Reports
ISSN
2045-2322
e-ISSN
2045-2322
Volume of the periodical
15
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
9
Pages from-to
29633
UT code for WoS article
001551303100013
EID of the result in the Scopus database
2-s2.0-105013534797