SoutheAsTern eUrope microciRculATION (SATURATION) registry - Design and rationale
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F25%3A10504111" target="_blank" >RIV/00064165:_____/25:10504111 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/25:00143804 RIV/00216208:11110/25:10504111
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=T0bhO_Ca-R" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=T0bhO_Ca-R</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.carrev.2024.11.012" target="_blank" >10.1016/j.carrev.2024.11.012</a>
Alternative languages
Result language
angličtina
Original language name
SoutheAsTern eUrope microciRculATION (SATURATION) registry - Design and rationale
Original language description
Background: A considerable number of symptomatic patients leave the cardiac catheterization lab without a definitive diagnosis for their symptoms because no epicardial stenoses are found. The significance of disorders of coronary microvasculature and vasomotion as the cause of symptoms and signs of ischemia has only recently been appreciated. Today we have a wide spectrum of invasive coronary physiology tools but little is known about when and how these tools are used in clinical practice. Study design and methodology: SoutheAsTern eUrope microciRculATION (SATURATION) registry will study the regional practice of patient selection for coronary function testing, indications, non-invasive ischemia testing, medications, procedural aspects of invasive physiology evaluation, and treatment changes after testing. The registry is expected to include 1600 patients in participating centers in Southeastern Europe from 2024 to 2029, using the thermodilution technique for evaluation of microcirculation. Major adverse cardiovascular events as well as patientcentered outcomes such as burden of angina and quality of life using Seattle Angina Questionnaire (SAQ) and EQ5D-5L will be recorded. The study will include patients with different stages of coronary artery disease (presence of disease or degree of stenosis) to elucidate the effect of coronary microcirculation on the outcomes in this broad group. Conclusion: The registry will provide information regarding the current practice of invasive coronary physiology assessment in populations at high cardiovascular risk in Southeastern Europe. This could lead to a better understanding of coronary microvascular dysfunction and its relationship to various degrees of coronary atherosclerosis together with potential interventions that can be beneficial.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
—
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cardiovascular Revascularization Medicine
ISSN
1553-8389
e-ISSN
1878-0938
Volume of the periodical
78
Issue of the periodical within the volume
September
Country of publishing house
US - UNITED STATES
Number of pages
4
Pages from-to
104-107
UT code for WoS article
001588316600001
EID of the result in the Scopus database
2-s2.0-85212339880