All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

The influence of age on clinical outcomes in patients treated with the resolute zotarolimus-eluting stent

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F16%3AN0000001" target="_blank" >RIV/00064173:_____/16:N0000001 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11120/16:43908129

  • Result on the web

    <a href="http://dx.doi.org/10.1002/ccd.25334" target="_blank" >http://dx.doi.org/10.1002/ccd.25334</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/ccd.25334" target="_blank" >10.1002/ccd.25334</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The influence of age on clinical outcomes in patients treated with the resolute zotarolimus-eluting stent

  • Original language description

    Aims: To evaluate the rate of clinical events and bleeding risk according to age in patients undergoing percutaneous coronary intervention (PCI) with new-generation drug-eluting stent enrolled in the RESOLUTE Global Clinical Program. Methods: This study represents a pooled analysis of 5 trials included in the RESOLUTE program including 5,130 patients, of whom 1675 (32.6%) were GREATER-THAN OR EQUAL TO70 years old (elderly patients). Results: After adjusting for confounders, age GREATER-THAN OR EQUAL TO70 years was a significant predictor of high mortality at 30 days (0.6% vs. 0.1%, P = 0.017) and two years (7.2% vs. 2%, P < 0.001). No differences were seen with respect to acute myocardial infarction (MI) or target lesion and vessel revascularization rates between young and elderly patients. Bleeding rates were higher in the elderly throughout follow-up. In the elderly, 7 out of 27 (26%) patients with bleeding episodes died, with a median time between bleeding episode to death of 21 days. In the younger population, 1 patient out of 17 with bleeding episode died (400 days later). Conclusion: Elderly patients undergoing PCI with a new-generation drug-eluting stent have an increased mortality and bleeding risk, with similar rates of acute MI and repeat revascularization. Bleeding risk was higher in the elderly and strongly related to death. TLF rates were not significantly different between the 2 age groups suggesting that the R-ZES is effective for patients younger and older than 70 years of age. R-ZES may be recommended for elderly patients when PCI with a DES is identified as a suitable option.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FA - Cardiovascular diseases including cardio-surgery

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    N - Vyzkumna aktivita podporovana z neverejnych zdroju

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Catheterization & Cardiovascular Interventions

  • ISSN

    1522-1946

  • e-ISSN

  • Volume of the periodical

    87

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    9

  • Pages from-to

    253-261

  • UT code for WoS article

    000370451700018

  • EID of the result in the Scopus database

    2-s2.0-84959482474