Detection of carotid artery stenosis using histological specimens: a comparison of CT angiography, magnetic resonance angiography, digital subtraction angiography and Doppler ultrasonography

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F16%3AN0000139" target="_blank" >RIV/00064173:_____/16:N0000139 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/16:10327481 RIV/00216208:11120/16:43911650 RIV/61383082:_____/16:00000109

Result on the web

<a href="http://dx.doi.org/10.1007/s00701-016-2842-0" target="_blank" >http://dx.doi.org/10.1007/s00701-016-2842-0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00701-016-2842-0" target="_blank" >10.1007/s00701-016-2842-0</a>

Result language

angličtina

Original language name

Detection of carotid artery stenosis using histological specimens: a comparison of CT angiography, magnetic resonance angiography, digital subtraction angiography and Doppler ultrasonography

Original language description

Background: Carotid endarterectomy (CEA) is accepted as a primary modality to treat carotid stenosis. The accuracy of measuring carotid stenosis is important for indication of the CEA procedure. Different diagnostic tools have been developed and used in the past 2 decades for the diagnosis of carotid stenosis. Only a few studies, however, have focused on the comparison of different diagnostic tools to histological findings of carotid plaque. Method: Patients with internal carotid artery (ICA) stenosis were investigated primarily by computed tomography angiography (CTA). Digital subtraction angiography (DSA), Doppler ultrasonography (DUS) and magnetic resonance angiography (MRA) were performed as well. Atherosclerotic plaque specimens were transversally cut into smaller segments and histologically processed. The slides were scanned and specimens showing maximal stenosis were determined; the minimal diameter and the diameter of the whole plaque were measured. High quality histological specimen and histological measurement was considered to be the prerequisite for inclusion into the analysis. The preoperative findings were compared with histological measurement. CTA and histological measurements were obtained from 152 patients. DSA measurements were available in 138 of these cases, MRA in 107 and DUS in 88. A comparison between preoperative and histological findings was performed. In addition, correlation coefficients were computed and tested. Results: A significant correlation was found for each of the diagnostic procedures. The strongest correlation coefficient and the best allocation of stenosis into clinical significant groups (<50 %, 50-69 %, GREATER-THAN OR EQUAL TO70 %) was observed for CTA.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

—

Project

<a href="/en/project/NT13627" target="_blank" >NT13627: Accuracy of CT Angiography, DSA, MRAg and DUS in carotid stenosis compared to histological specimen</a><br>

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta Neurochirurgica

ISSN

0001-6268

e-ISSN

—

Volume of the periodical

158

Issue of the periodical within the volume

8

Country of publishing house

AT - AUSTRIA

Number of pages

10

Pages from-to

1505-1514

UT code for WoS article

000379340100012

EID of the result in the Scopus database

2-s2.0-84973165254