The V6-V1 interpeak interval: a novel criterion for the diagnosis of left bundle branch capture

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F22%3A43921795" target="_blank" >RIV/00064173:_____/22:43921795 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11120/22:43921795

Result on the web

<a href="https://doi.org/10.1093/europace/euab164" target="_blank" >https://doi.org/10.1093/europace/euab164</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/europace/euab164" target="_blank" >10.1093/europace/euab164</a>

Result language

angličtina

Original language name

The V6-V1 interpeak interval: a novel criterion for the diagnosis of left bundle branch capture

Original language description

AIMS: We hypothesized that during left bundle branch (LBB) area pacing, the various possible combinations of direct capture/non-capture of the septal myocardium and the LBB result in distinct patterns of right and left ventricular activation. This could translate into different combinations of R-wave peak time (RWPT) in V1 and V6. Consequently, the V6-V1 interpeak interval could differentiate the three types of LBB area capture: non-selective (ns-)LBB, selective (s-)LBB, and left ventricular septal (LVS). METHODS AND RESULTS: Patients with unquestionable evidence of LBB capture were included. The V6-V1 interpeak interval, V6RWPT, and V1RWPT were compared between different types of LBB area capture. A total of 468 patients from two centres were screened, with 124 patients (239 electrocardiograms) included in the analysis. Loss of LVS capture resulted in an increase in V1RWPT by &gt;=15 ms but did not impact V6RWPT. Loss of LBB capture resulted in an increase in V6RWPT by &gt;=15 ms but only minimally influenced V1RWPT. Consequently, the V6-V1 interval was longest during s-LBB capture (62.3 +- 21.4 ms), intermediate during ns-LBB capture (41.3 +- 14.0 ms), and shortest during LVS capture (26.5 +- 8.6 ms). The optimal value of the V6-V1 interval value for the differentiation between ns-LBB and LVS capture was 33 ms (area under the receiver operating characteristic curve of 84.7%). A specificity of 100% for the diagnosis of LBB capture was obtained with a cut-off value of &gt;44 ms. CONCLUSION: The V6-V1 interpeak interval is a promising novel criterion for the diagnosis of LBB area capture.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

EP Europace

ISSN

1099-5129

e-ISSN

1532-2092

Volume of the periodical

24

Issue of the periodical within the volume

1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

8

Pages from-to

40-47

UT code for WoS article

000743688600009

EID of the result in the Scopus database

2-s2.0-85118588119