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Long-term follow-up of VIALE-C in patients with untreated AML ineligible for intensive chemotherapy

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F22%3A43923889" target="_blank" >RIV/00064173:_____/22:43923889 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11120/22:43923889

  • Result on the web

    <a href="https://doi.org/10.1182/blood.2022016963" target="_blank" >https://doi.org/10.1182/blood.2022016963</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1182/blood.2022016963" target="_blank" >10.1182/blood.2022016963</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Long-term follow-up of VIALE-C in patients with untreated AML ineligible for intensive chemotherapy

  • Original language description

    Venetoclax (VEN) in combination with low-dose cytarabine (LDAC) is FDA-approved for the treatment of unfit patients with newly diagnosed AML ineligible for intensive chemotherapy, based on a response rate of 54% (complete remission with or without blood count recovery [CR/CRi]) in the original phase Ib/II study.1 The VIALE-C phase 3 study (ClinicalTrials.gov Identifier: NCT03069352), compared VEN vs placebo (PBO) in combination with LDAC in 211 patients with untreated AML ineligible for intensive chemotherapy.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30205 - Hematology

Result continuities

  • Project

  • Continuities

    N - Vyzkumna aktivita podporovana z neverejnych zdroju

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Blood

  • ISSN

    0006-4971

  • e-ISSN

    1528-0020

  • Volume of the periodical

    140

  • Issue of the periodical within the volume

    25

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    3

  • Pages from-to

    2754-2756

  • UT code for WoS article

    000922749800001

  • EID of the result in the Scopus database

    2-s2.0-85142159148