Feasibility and safety of left bundle branch area pacing-cardiac resynchronization therapy in elderly patients
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F23%3A43923058" target="_blank" >RIV/00064173:_____/23:43923058 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/23:43923058 RIV/00216208:11150/23:10441801 RIV/00179906:_____/23:10441801
Result on the web
<a href="https://doi.org/10.1007/s10840-022-01174-4" target="_blank" >https://doi.org/10.1007/s10840-022-01174-4</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10840-022-01174-4" target="_blank" >10.1007/s10840-022-01174-4</a>
Alternative languages
Result language
angličtina
Original language name
Feasibility and safety of left bundle branch area pacing-cardiac resynchronization therapy in elderly patients
Original language description
BACKGROUND: Left bundle branch area pacing (LBBAP) is an emerging technique to achieve cardiac resynchronization therapy (CRT), but its feasibility and safety in elderly patients with heart failure with reduced ejection fraction and left bundle branch block is hardly investigated. METHODS: We enrolled consecutive patients with an indication for CRT comparing pacing parameters and complication rates of LBBAP-CRT in elderly patients (>= 75 years) versus younger patients (< 75 years) over a 6-month follow-up. RESULTS: LBBAP was successful in 55/60 enrolled patients (92%), among which 25(45%) were elderly. In both groups, LBBAP significantly reduced the QRS duration (elderly group: 168 +- 15 ms to 136 +- 12 ms, p < 0.0001; younger group: 166 +- 14 ms to 134 +- 11 ms, p < 0.0001) and improved LVEF (elderly group: 28 +- 5% to 40 +- 7%, p < 0.0001; younger group: 29 +- 5% to 41 +- 8%, p < 0.0001). The pacing threshold was 0.9 +- 0.8 V in the elderly group vs. 0.7 +- 0.5 V in the younger group (p = 0.350). The R wave was 9.5 +- 3.9 mV in elderly patients vs. 10.7 +- 2.7 mV in younger patients (p = 0.341). The fluoroscopic (elderly: 13 +- 7 min vs. younger: 11 +- 7 min, p = 0.153) and procedural time (elderly: 80 +- 20 min vs. younger: 78 +- 16 min, p = 0.749) were comparable between groups. Lead dislodgement occurred in 2(4%) patients, 1 in each group (p = 1.000). Intraprocedural septal perforation occurred in three patients (5%), 2(8%) in the elderly group (p = 0.585). One patient (2%) in the elderly group had a pocket infection. CONCLUSIONS: LBBAP is a feasible and safe technique for delivering physiological pacing in elderly patients who are candidates for CRT with suitable pacing parameters and low complication rates.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Interventional Cardiac Electrophysiology
ISSN
1383-875X
e-ISSN
1572-8595
Volume of the periodical
66
Issue of the periodical within the volume
2
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
11
Pages from-to
311-321
UT code for WoS article
000766408000001
EID of the result in the Scopus database
2-s2.0-85126010256