Efficacy of Platelet-Rich Plasma versus Mesotherapy with Recombinant Growth Factors and Stem Cell-Conditioned Media in Androgenetic Alopecia: A Retrospective Study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F24%3A43927196" target="_blank" >RIV/00064173:_____/24:43927196 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11120/24:43927196

Result on the web

<a href="https://doi.org/10.1159/000539105" target="_blank" >https://doi.org/10.1159/000539105</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1159/000539105" target="_blank" >10.1159/000539105</a>

Result language

angličtina

Original language name

Efficacy of Platelet-Rich Plasma versus Mesotherapy with Recombinant Growth Factors and Stem Cell-Conditioned Media in Androgenetic Alopecia: A Retrospective Study

Original language description

Introduction: Androgenetic alopecia (AGA) is the most common type of hair loss. Platelet-rich plasma (PRP) and mesotherapy (MZT) injections of various solutions fortified with growth factors are popular treatment options for AGA. The aim of this study was to compare the efficacy of RPP and MZT products in the treatment of AGA. Methods: This retrospective study included 72 AGA patients treated with two PRP formulations and two MZT products, administered manually or with a gun injector. Hair parameters (hair thickness, hair density, and hair count) on frontal and vertex areas were measured before and after 6 months. Results: Over 6 months, trichoscopic parameters showed significant intragroup and intergroup variability. MZT1 and PRP2 groups exhibited statistically significant improvement in most parameters, while MZT2 significantly increased vertex hair density. Hair thickness changes differed significantly between PRP1 and PRP2 groups (unadjusted p value &lt;0.001) and possibly between MZT1 and PRP1 groups (unadjusted p value = 0.049) in both regions. Discussion: Injections of PRP and MZT formulations can significantly enhance trichoscopic parameters in AGA patients within a 6-month period, but the extent of improvement varies among different PRP and MZT products.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30216 - Dermatology and venereal diseases

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Skin Appendage Disorders

ISSN

2296-9195

e-ISSN

2296-9160

Volume of the periodical

10

Issue of the periodical within the volume

5

Country of publishing house

CH - SWITZERLAND

Number of pages

7

Pages from-to

376-382

UT code for WoS article

001243074400001

EID of the result in the Scopus database

2-s2.0-85195652871