Correlation of MRI- evaluated degenerative disc disease with positivity on Single-Photon Emission Computed Tomography Imaging in patients with chronic low back pain
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F24%3A43927423" target="_blank" >RIV/00064173:_____/24:43927423 - isvavai.cz</a>
Alternative codes found
RIV/61383082:_____/24:00001401 RIV/00216208:11110/24:10482326 RIV/00216208:11120/24:43927423 RIV/00064203:_____/24:10482326
Result on the web
<a href="https://doi.org/10.1016/j.wneu.2024.07.163" target="_blank" >https://doi.org/10.1016/j.wneu.2024.07.163</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.wneu.2024.07.163" target="_blank" >10.1016/j.wneu.2024.07.163</a>
Alternative languages
Result language
angličtina
Original language name
Correlation of MRI- evaluated degenerative disc disease with positivity on Single-Photon Emission Computed Tomography Imaging in patients with chronic low back pain
Original language description
PURPOSE: Chronic low back pain (CLBP), affecting up to 58% of the population, often stems from intervertebral disc degeneration. Although magnetic resonance imaging (MRI) is commonly used for diagnostics, challenges arise in pinpointing pain sources due to frequent asymptomatic findings. Single-photon emission tomography (SPECT) integrated with computed tomography (CT) offers a promising approach, enhancing sensitivity and specificity. METHODS: In this retrospective study, spanning 2016 to 2022, SPECT/CT imaging was performed on 193 patients meeting specific criteria. We correlated SPECT/CT findings with lumbar MRI results, utilizing Pfirrmann and Rajasekaran classifications for disc degeneration and endplate damage assessment. Logistic regression analysis adjusted for age and sex evaluated associations. RESULTS: Of 965 spinal levels assessed, SPECT/CT positivity strongly correlated with higher Pfirrmann grades and Rajasekaran endplate classifications. Notably, Modic changes on MRI displayed a non-significant relationship with SPECT/CT positivity. Significant associations were observed in older patients with positive Modic changes, Pfirrmann grades, and Rajasekaran classifications. CONCLUSION: This comprehensive study, the largest of its kind, establishes a significant link between SPECT/CT positivity and advanced lumbar degenerative changes. Higher Pfirrmann grades and increased Rajasekaran endplate damage demonstrated substantial correlations with SPECT/CT positivity. Notably, Modic changes did not exhibit such association. Our findings underscore the potential of SPECT/CT in identifying pain generators in degenerative spinal conditions, offering valuable insights for future interventions.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30224 - Radiology, nuclear medicine and medical imaging
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
World Neurosurgery
ISSN
1878-8750
e-ISSN
1878-8769
Volume of the periodical
190
Issue of the periodical within the volume
October
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
"e504"-"e512"
UT code for WoS article
001338768900001
EID of the result in the Scopus database
2-s2.0-85202214125