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Do lumbar magnetic resonance imaging changes predict neuropathic pain in patients with chronic non-specific low back pain?

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F19%3A00070685" target="_blank" >RIV/65269705:_____/19:00070685 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/19:00109783

  • Result on the web

    <a href="https://journals.lww.com/md-journal/fulltext/2019/04260/Do_lumbar_magnetic_resonance_imaging_changes.79.aspx" target="_blank" >https://journals.lww.com/md-journal/fulltext/2019/04260/Do_lumbar_magnetic_resonance_imaging_changes.79.aspx</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1097/MD.0000000000015377" target="_blank" >10.1097/MD.0000000000015377</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Do lumbar magnetic resonance imaging changes predict neuropathic pain in patients with chronic non-specific low back pain?

  • Original language description

    The aim of this observational, cross-sectional study was to analyse lumbar magnetic resonance imaging (MRI) findings in patients with non-specific chronic low back pain (CLBP), and to evaluate any correlation with pain intensity and their capacity to predict neuropathic pain (NP) in these patients. Fifty-two patients with non-specific CLBP, between 21 and 62 years of age, 50% men, were investigated. Lumbar MRI was employed to assess disc degeneration, endplate changes, Modic changes, disc displacement, facet degeneration, foraminal stenosis and central lumbar spinal stenosis. The characteristics of pain were evaluated and patients were divided into 2 subgroups: with NP (24 patients) and without NP (28 patients), based on the results of a DN4-interview. Correlations between particular MRI changes and their relations to the intensity of pain were evaluated. Logistic regression was used to disclose predictors of NP. Lumbar spine degenerative features were frequent in patients with non-specific CLBP, with L4/5 the most affected level. A significant correlation emerged between the severity of degenerative changes in particular lumbar spine structures (correlation coefficient ranging between 0.325 and 0.573), while no correlation was found between severity of degenerative changes and pain. Multivariate logistic regression revealed only 2 independent predictors of NP -female sex (odds ratio [OR]=11.9) and a mean pain intensity of &gt;= 4.5 in the previous 4 weeks (OR=13.1). Degenerative changes in the lumbar spine are frequent MRI findings, but do not correlate with the intensity of pain and do not predict NP. However, female sex and pain intensity do predict NP.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30218 - General and internal medicine

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Medicine

  • ISSN

    0025-7974

  • e-ISSN

  • Volume of the periodical

    98

  • Issue of the periodical within the volume

    17

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    9

  • Pages from-to

    "e15377"

  • UT code for WoS article

    000467337400079

  • EID of the result in the Scopus database